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Prolidase deficiency: A patient without hydroxyproline-containing iminodipeptides in urine

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Journal of Inherited Metabolic Disease

Summary

A 17-year-old girl was shown to have prolidase deficiency on the basis of the presence of large amounts of proline-containing dipeptides in urine and an almost complete absence of prolidase in plasma and erythrocytes. Unlike most earlier cases of this genetic defect our patient did not excrete hydroxyproline-containing dipeptides in her urine.

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Authors and Affiliations

  1. Endocrine Research Laboratory, Department of Obstetrics and Gynaecology, The University of Western Australia, King Edward Memorial Hospital for Women, 374 Bagot Road, 6008, Subiaco, Western Australia

    S. J. Wysocki & R. Hahnel

  2. Department of Clinical Chemistry, Princess Margaret Hospital for Children, Thomas Street, 6008, Subiaco, Western Australia

    T. Mahoney & R. G. Wilson

  3. Department of Internal Medicine, Royal Perth Hospital, 197 Wellington Street, 6000, Perth, Western Australia

    P. K. Panegyres

Authors
  1. S. J. Wysocki
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  2. R. Hahnel
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  3. T. Mahoney
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  4. R. G. Wilson
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  5. P. K. Panegyres
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Wysocki, S.J., Hahnel, R., Mahoney, T. et al. Prolidase deficiency: A patient without hydroxyproline-containing iminodipeptides in urine. J Inherit Metab Dis 11, 161–165 (1988). https://doi.org/10.1007/BF01799866

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  • DOI: https://doi.org/10.1007/BF01799866

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