Surgical and Radiologic Anatomy

, Volume 14, Issue 3, pp 223–226 | Cite as

Fetal development of the pyloric muscle

  • D Bourdelat
  • J P Barbet
  • J P Chevrel
Original Articles

Summary

The fetal development of the pyloric muscle was studied in five human embryos (crown-rump length 5 to 31 mm) and in ten fetuses aged 3 to 9 months. Samples of pyloric muscle were obtained during operation for pyloric stenosis in two infants aged six weeks. Anatomo-radiologic, morphologic and immunohistochemical studies were made on this material, from which it emerged that the pylorus is identifiable by means of specific markers from the 40th day. Its two-layered muscular structure is described in detail. The mechanism of sphincteric function is reviewed. This study assumes clicincal importance in the context of the etiopathogenesis of hypertrophic stenosis of the pylorus.

Keywords

Stomach Pylorus Pyloric muscle 

Développement foetal du muscle pylorique

Résumé

Le développement foetal du muscle pylorique a été étudié chez cinq embryons humains (taille VC 5 à 31 mm) et dix foetus âgés de 3 à 9 mois. Des prélèvements de muscle pylorique ont été effectués en cours d'intervention chirurgicale pour sténose du pylore chez deux nourrissons de six semaines. Des études anatomo-radiologiques, morphologiques et immunocytochimiques ont été effectuées sur ce matériel au terme desquelles il apparait que le pylore est identifiable à l'aide de marqueurs spécifiques dès le 40ème jour. Sa structure musculaire en deux couches est décrite en détail. Le mécanisme de la fonction sphinctérienne est rappelé. Ce travail trouve son application clinique dans l'analyse étiopathogénique de la sténose hypertrophique du pylore.

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Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • D Bourdelat
    • 1
  • J P Barbet
    • 2
  • J P Chevrel
    • 1
  1. 1.Laboratoire d'Anatomie, UER BobignyUniversité Paris XIIIBobignyFrance
  2. 2.Laboratoire de Pathologie PédiatriqueHôpital Saint Vincent de PaulParisFrance

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