Summary
A survey is given on the history of the discovery of the blood-brain barrier, of its functions and of its clinical importance. Also attempts to circumvent or disrupt the barrier with the aim of introducing therapeutic or diagnostic agents into the brain tissue have been reported. Finally the possible negative effects of lasting barrier defects in transplanted foet al tissue are mentioned.
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Go, K.G. The neurosurgeon and the blood-brain barrier. A survey. Acta neurochir 95, 25–27 (1988). https://doi.org/10.1007/BF01793078
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DOI: https://doi.org/10.1007/BF01793078