Genetica

, Volume 40, Issue 1, pp 65–83 | Cite as

Über die cytogenetische Wirkung dreier Monoterpene, eines Anthrachinons und eines Tropolons auf die Mitose vonVicia faba

  • E. Schmid
Article

Abstract

The cytogenetic effects of three terpenes, a tropolone, and an anthraquinone on mitosingVicia faba cells were investigated. The three terpenes (α+β) thujone, thujylic alcohol, sabinene), and the tropolone (β-thujaplicin), induce partial or complete failure of the spindle apparatus. In addition, the terpenes induce tripolar mitoses; the tropolone and the terpenes (except sabinene) induce chromosomal stickiness; thujaplicin, thujone and the anthraquinone (aloe-emodin-glucoside) induce chromosomal aberrations. The latter in particular causes subchromatid breaks and rearrangements. The present results and the extensive data in the literature indicate that the effects of the tropolones and terpenes, can be related to their structure. No such relationship could be deduced for the anthraquinones.

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Literatur

  1. Bacq, Z. (1958). Grundlagen der Strahlenbiologie. Georg Thieme Verlag, Stuttgart.Google Scholar
  2. Barthelmess, A. (1957). Chemisch induzierte multipolare Mitosen.Protoplasma 48: 645–651.Google Scholar
  3. Barthelmess, A. &J. Einlechner (1960). Chemisch induzierte multipolare Mitosen II.Protoplasma 51: 325–337.Google Scholar
  4. Barthelmess, A. &A. Elkabarity (1963). Chemisch induzierte multipolare Mitosen III.Protoplasma 54: 455–475.Google Scholar
  5. Conger, A. D.. (1965). The fate of metaphase aberrations.Radiat. Bot. 5: 81–86.Google Scholar
  6. Davidson, D. (1957). The irradiation of dividing cells. I. The effects of X-rays on prophase chromosomes.Chromosoma 9: 39–60.PubMedGoogle Scholar
  7. Fitzgerald, P. H. (1961). Mitosis in partially pycnotic, HeLa cells.Exptl. Cell Res. 24: 584–588.PubMedGoogle Scholar
  8. Hadder, J. C. &G. B. Wilson (1958). Cytological assay of c-mitotic and prophase poison actions.Chromosoma 9: 91–104.PubMedGoogle Scholar
  9. Hörhammer, L., L. Farkas, H. Wagner &E. Müller (1964). Synthese und Strukturbeweis des Aloe-Emodin-8-mono-ß-D-glucosid ausRheum palmatum var.tangut. Chem. Berichte 97: 1662–1665.Google Scholar
  10. LaCour, L. F. &A. Rutishauser (1953). Chromosome breakage experiments with endosperm: sub-chromatid breakage.Nature 172: 501.Google Scholar
  11. LaCour, L. F. &A. Rutishauser (1954). X-rays, breakage experiments with endosperm. 1. sub-chromatid breakage.Chromosoma 6: 696–709.PubMedGoogle Scholar
  12. Levan, A. &H. J. Tjio (1948). Induction of chromosome fragmentation by phenols.Hereditas 34: 452–484.Google Scholar
  13. Natarajan, A. T. &M. D. Upadhya (1964). Localized chromosome-breakage induced by ethyl-methane-sulfate and hydroxylamine inVicia faba.Chromosoma 15: 156–169.PubMedGoogle Scholar
  14. Östergren, G. (1944). Colchicine mitosis, chromosome contraction, narcosis and protein chain folding.Hereditas 30: 429–467.Google Scholar
  15. Östergren, G. &T. Wakonig (1954a). A sensitive period at the chromosome breakage activity of coumarin. Proc. IX. Internat. Congr,. Genet.Caryologia 6: (Suppl.): 838–839.Google Scholar
  16. Östergren, G. &T. Wakonig (1954b). True or apparent subchromatid breakage and the induction of labile states in cytological chromosome loci.Bot. Not. 4: 357–375.Google Scholar
  17. Resende, F. &M. Manarte (1951). Physiological changes as the cause of mutations.Portug. Acta biol. 3: 219–233.Google Scholar
  18. Revell, S. H. (1953). Chromosome breakage by X-rays and radiomimetic substances inVicia.Heredity 6 (Suppl.): 107–124.Google Scholar
  19. Sato, K. &K. Akaishi (1951). Effect of tropolone and related compounds (compound having unsaturated seven membered ring structure) on Yoshida sarcoma.Gann. 42: 150–151.Google Scholar
  20. Schmid, E. (1967). Untersuchungen über die cytologische Wirkung einiger Bestandteile pflanzlicher Abortiva der Volksmedizin. (Dissertation, München).Google Scholar
  21. Shimizu, Y. (1962). Effects of chemicals on the mitotic cell in plant, with special reference to tropoids.Sci. Rep. Tohoku Univ., Ser 4,28: 143–180.Google Scholar
  22. Siebs, W. (1963). Mitoseablaufstörungen: III. Zur Wirkung von Vincaleukoblastin auf normale und maligne Zellen in vitro.Zeitschrift f. Zellforsch. 61: 231–275.Google Scholar
  23. Taylor, E. W. (1959). Dynamics of spindle formation and its inhibition by chemicals.J. Bioph. Biochem Cytol. 6: 193–196.Google Scholar
  24. Wada, B. (1952). The effect of chemicals on mitosis studied inTradescantia cells in vivo. I. p-acethylaminotropolone.Cytologia 17: 14–34.Google Scholar

Copyright information

© Martinus Nijhoff 1969

Authors and Affiliations

  • E. Schmid
    • 1
  1. 1.Botanisces Institut der Universität MünchenMünchenDeutschland

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