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Antimicrobial drug utilisation in hospitals in Italy and other European countries

Antibiotikaanwendung im Krankenhaus in Italien und anderen europäischen Ländern

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Summary

Antibiotic prescribing patterns in hospitals are analysed in this review of three drug utilisation studies conducted in six European countries, with special emphasis to the third-generation cephalosporins. A great variability in the use of antimicrobial drugs is evident, both between countries and between hospitals in the same country. This variability is found also between patients with the same infectious disease. The possible reasons for these differences are discussed and a strategy to modify the hospital drugs prescribing is suggested.

Zusammenfassung

In dieser Übersicht dreier Anwendungsstudien von Antibiotika, die in sechs europäischen Ländern durchgeführt wurde, werden die verordneten Wirkungsspektren unter besonderer Berücksichtigung der Cephalosporine der dritten Generation analysiert. Eine große Variabilität in antimikrobiellen Substanzen, sowohl unter den Ländern als auch von Krankenhaus zu Krankenhaus ist offensichtlich. Diese Unterschiede sind ebenso augenfällig bei Patienten mit gleichartigen Infektionen. Die möglichen Gründe für diese Unterschiede werden geschildert und eine Strategie zur Modifizierung der Verordnung von Chemotherapeutika wird vorgeschlagen.

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References

  1. WHO: Studies in drug utilization. Copenhagen WHO Regional Publications, European Series 8 (1979).

  2. WHO: The selection of essential drugs. WHO Technical Report Series 615 (1977).

  3. Garattini, S., Tognoni, G. Drug utilization review and pharmacoeconomics: interaction after parallel development? Pharmacoeconomics 4 (1993) 162–172.

    PubMed  Google Scholar 

  4. Ioannides-Demos, L. L., Eckert, G. M., Mac-Lean, A. J. Pharmacoeconomic consequences of measurement and modification of hospital drug use. Pharmacoeconomics 2 (1993) 15–33.

    Google Scholar 

  5. Sacrestàn, J. A., Soto, J. Drug utilization studies as tools in health economics. Pharmacoeconomics 5 (1994) 299–312.

    PubMed  Google Scholar 

  6. Blackborn, J. L. Impact of drug usage review on drug utilization. Pharmacoeconomics 3 (1993) 14–21.

    PubMed  Google Scholar 

  7. Martini, N., Scroccaro, G., Sala, M. L., Olivencia, P. Antiinfective consumption in a group of hospitals in three Mediterranean countries. In:Muller, N. F., Hekster, Y. A. (eds.): Progress in clinical pharmacy. European Society of Clinical Pharmacy, Noordwijk, The Netherlands, 1990, pp. 220–221.

    Google Scholar 

  8. Janknegt, R., Wijnands, W. J. A., Caprassa, M., Brandenburg, W., Schmitenmaker, M. G., Stobberingh, E. Antimicrobial drug use in hospitals in The Netherlands, Germany and Belgium. Eur. J. Clin. Microbiol. Infect. Dis. 12 (1993) 832–838.

    PubMed  Google Scholar 

  9. Guglielmo, L., Leone, R., Moretti, U., Conforti, A., Spolaor, A., Velo, G. P. Antibiotic prescribing patterns in Italian hospital inpatients with pneumonia, chronic obstructive pulmonary disease and urinary tract infections. DICP Ann. Pharmacother. 27 (1993) 18–22.

    Google Scholar 

  10. Davery, P. G., Malek, M. M., Parker, S. E. Pharmacoeconomics of antimicrobial treatment. Pharmacoeconomics 1 (1992) 409–437.

    PubMed  Google Scholar 

  11. Norrby, S. R. Pharmacoeconomic studies on antibiotics. Current controversies. Pharmacoeconomics 5 (1994) 274–277.

    PubMed  Google Scholar 

  12. Kunin, C. M. Rational use of antibiotics. WHO Drug Information 4 (1990) 4–7.

    Google Scholar 

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Guglielmo, L., Leone, R., Moretti, U. et al. Antimicrobial drug utilisation in hospitals in Italy and other European countries. Infection 22 (Suppl 3), S176–S181 (1994). https://doi.org/10.1007/BF01782703

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