Summary
Antibiotic prescribing patterns in hospitals are analysed in this review of three drug utilisation studies conducted in six European countries, with special emphasis to the third-generation cephalosporins. A great variability in the use of antimicrobial drugs is evident, both between countries and between hospitals in the same country. This variability is found also between patients with the same infectious disease. The possible reasons for these differences are discussed and a strategy to modify the hospital drugs prescribing is suggested.
Zusammenfassung
In dieser Übersicht dreier Anwendungsstudien von Antibiotika, die in sechs europäischen Ländern durchgeführt wurde, werden die verordneten Wirkungsspektren unter besonderer Berücksichtigung der Cephalosporine der dritten Generation analysiert. Eine große Variabilität in antimikrobiellen Substanzen, sowohl unter den Ländern als auch von Krankenhaus zu Krankenhaus ist offensichtlich. Diese Unterschiede sind ebenso augenfällig bei Patienten mit gleichartigen Infektionen. Die möglichen Gründe für diese Unterschiede werden geschildert und eine Strategie zur Modifizierung der Verordnung von Chemotherapeutika wird vorgeschlagen.
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Guglielmo, L., Leone, R., Moretti, U. et al. Antimicrobial drug utilisation in hospitals in Italy and other European countries. Infection 22 (Suppl 3), S176–S181 (1994). https://doi.org/10.1007/BF01782703
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DOI: https://doi.org/10.1007/BF01782703