Summary
Clinical features of nosocomial bacteremias due to methicillin-resistantStaphylococcus aureus (MRSA) (M group, n=71) andPseudomonas aeruginosa (P group, n=25) in a university hospital during 1982–1993 were retrospectively analyzed. The majority of these patients had an underlying disease, and bacteremia occurred in hospital. There were no differences in the male to female ratio and the mean age of the patients between the two groups. The ratio of medical wards to surgical wards was higher in the P group (18/7=2.6) than for the M group (38/33=1.2).P. aeruginosa was more frequently isolated from patients with hematological malignancies and MRSA with solid tumors. The percentage of MRSA among gram-positive bacteremia and ofP. aeruginosa among gram-negative bacteria has shown a tendency to increase in recent years, and antibiotic sensitivity of these two organisms showed, on a whole, a tendency to decrease. Attention should be called to the increase of these two pathogens.
Zusammenfassung
In einer retrospektiven Analyse wurden die klinischen Charakteristika der von 1982–1993 in einer Universitätsklinik aufgetretenen nosokomialen Bakteriämien durch methicillinresistenteStaphylococcus aureus (MRSA) (Gruppe M n=71) und durchPseudomonas aeruginosa (Gruppe P=25) analysiert. Es handelte sich in den meisten Fällen um nosokomiale Infektionen bei Patienten mit Grundkrankheiten. Unterschiede zwischen den beiden Gruppen hinsichtlich Geschlechtsverteilung und dem mittleren Alter der Patienten fanden sich nicht. Das Verhältnis internistische Stationen zu chirurgischen Stationen war in Gruppe P mit 18/7=2,6 höher als in Gruppe M mit 38/33=1,2.P. aeruginosa wurde häufiger bei Patienten mit hämatologischen Grunderkrankungen isoliert und MRSA bei Patienten mit soliden Tumoren. In den letzten Jahren ist ein tendenzielles Ansteigen des Anteils von MRSA unter den grampositiven und vonP. aeruginosa unter den gramnegativen Bakterien und eine insgesamt abnehmende Antibiotikaempfindlichkeit zu beobachten. Die Zunahme dieser beiden Erreger verdient Wachsamkeit.
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Mizushima, Y., Li, H., Sassa, K. et al. Nosocomial septicemias due to methicillin-resistantStaphylococcus aureus andPseudomonas aeruginosa in a university hospital over a 12-year period — The same intractable infections. Infection 24, 238–241 (1996). https://doi.org/10.1007/BF01781100
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DOI: https://doi.org/10.1007/BF01781100