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In vivo localized1 H spectroscopy of the rat eye at 7 T: preliminary studies

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Abstract

Preliminaryin vivo proton spectroscopic studies of the posterior chamber of the rat eye have been undertaken at 7 T. The Spatial and Chemical shift encoded Excitation (SPACE) localization sequence was used to acquire signals from 10-µl voxels and demonstrate the presence of metabolites associated with the vitreous humor, lens, retina, and the optic nerve. LocalizedT 2 andT 1 measurements of water in the vitreous humor indicate a relatively fluid environment. Susceptibility maps are used to demonstrate the difficulties ofin vivo spectroscopic investigations in the anterior regions of the eye. Comments are made concerning the implications for spectral resolution in these regions.

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  1. Centre for Magnetic Resonance, University of Queensland, 4072, St Lucia, Queensland, Australia

    Stuart Crozier & David M. Doddrell

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  1. Stuart Crozier
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  2. David M. Doddrell
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Crozier, S., Doddrell, D.M. In vivo localized1 H spectroscopy of the rat eye at 7 T: preliminary studies. MAGMA 3, 137–141 (1995). https://doi.org/10.1007/BF01771698

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  • DOI: https://doi.org/10.1007/BF01771698

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