The effect of temperature on MR relaxation times and signal intensities for human tissues
T1 andT2 relaxation times were measured on human tissue samples of adipose tissue, muscle, bone marrow and osteolytic skeletal metastases at temperatures ranging from +37°C to −10°C. Relative signal intensities forT1, proton density andT2-weighted imaging sequences were also calculated.T1 andT2 of adipose tissue decreased almost linearly with decreasing temperature while for muscle, bone marrow and metastasesT1 andT2 decreased slightly to moderately, with temperature reduction to about −5 °C at which temperature a sudden marked decrease occurred. Calculated signal intensities showed a decrease in image contrast with temperature reduction and reversal of contrast between adipose tissue and the other tested tissues with all imaging sequences at temperatures around 0°C.
Keywordsmr imaging human tissues tissue temperature mr relaxation time changes mr signal intensity changes
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