Abstract
Purpose: To evaluate the feasibility of MRI-based myocardial first-pass contrast perfusion imaging with a multi-shot echo planar imaging (EPI) technique.
Subjects and methods: A non-sequential (ECG-triggered) gradient echo two-shot EPI acquisition strategy capable of covering the entire heart in contiguous 10-mm sections every two cardiac cycles with an in-plane resolution of 1.56 × 1.56 mm was implemented on a 1.5-T Signa Advantage Scanner equipped with prototype hardware for non-resonant EPI in the transverse plane. The heart of a single volunteer was studied prior to and following the intravenous bolus application of a paramagnetic contrast agent (Gd-DOTA, 0.2 mmol/kg).
Results: Twelve contiguous transaxial 10-mm EPI images were obtained every two RR intervals for a total of 40 s. The myocardial contrast perfusion study was technically adequate. Contrast caused a signal loss of 87% in the right and 67% in the left ventricle and 59% in the myocardium.
Conclusion: First-pass myocardial perfusion imaging with a gradient echo, two-shot echo planar imaging strategy is feasible.
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This work has been supported in part by SNF grant 32-2549.88 and KWF grant 2194.1.
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Debatin, J.E., McKinnon, G.C. & v. Schulthess, G.K. Technical note—Approach to myocardial perfusion with echo planar imaging. MAGMA 4, 7–11 (1996). https://doi.org/10.1007/BF01759774
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DOI: https://doi.org/10.1007/BF01759774