Skip to main content
SpringerLink
Log in

Makromolekulare Datenverarbeitung im Zentralnervensystem

  • Published:
Klinische Wochenschrift Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Schmitt, F. O.: The physicla basis of the and learning. Science149, No 3687, 931–936 (1965).

    Google Scholar 

  2. Schmitt, F. O.: The biomedical communication problem. Technol. Rev. (M.I.T.)66, No 5, 13–15ff. (1964).

    Google Scholar 

  3. Katchalsky, A., andA. Oplatka: Hysteresis and macromolecular memory. Neurosci. Res. Progr. Bull.4, Suppl., 71–93 (1966).

    Google Scholar 

  4. Lashley, K. S.: In search of the engram. In: Society of experimental biology symposium No 4: Physiological mechanism in animal behavior (J. F. Danielli andR. Brown, eds.), p. 454–482. London: Cambridge University Press 1950.

    Google Scholar 

  5. McConnell, J. V., A. L. Jacobson, andD. P. Kimble: The effects of regeneration upon retention of a conditioned response in the planarian. J. comp. physiol. Psychol.52, 1–5 (1959).

    Google Scholar 

  6. Gaito, J. (ed.): Macromolecules and behavior. New York: Appleton-Century-Crofts 1966.

    Google Scholar 

  7. Hydén, H. V.: Biochemical changes accompanying learning. In: The neurosciences — a study program (G. C. Quarton, T. Melnechuk, andF. O. Schmitt, eds.). New York: Rockefeller University Press (in press).

  8. Hydén, H., andE. Egyházi: Changes in RNA content and base composition in cortical neurons of rats in a learning experiment involving transfer of handedness. Proc. nat. Acad. Sci. (Wash.)52, 1030–1035 (1964).

    Google Scholar 

  9. Hydén, H.: Personal communication.

  10. Flexner, L. B., andJ. B. Flexner: Effect of acetoxycycloheximide and of an acetoxycyclohex-imide-puromycin mixture on cerebral protein synthesis and memory in mice. Proc. nat. Acad. Sci. (Wash.)55, 369–374 (1966).

    Google Scholar 

  11. Agranoff, B. W., andP. D. Klinger: Puromycin effect on memory fixation in the goldfish. Science146, 952–953 (1964).

    Google Scholar 

  12. Agranoff, B. W.: Agents that block memory. In: The neurosciences — a study program, op. cit.

  13. Barondes, S. H., andM. R. Jarvik: The influence of actinomycin-D on brain RNA synthesis and on memory. J. Neurochem.11, 187–195 (1964).

    Google Scholar 

  14. Glasky, A. J., andL. N. Simon: Magnesium pemoline: enhancement of brain RNA polymerases. Science151, 702–703 (1966).

    Google Scholar 

  15. Avery, O. T., C. M. MacLeod, andM. McCarty: Studies on the chemical nature of the substance inducing transformation of pneumococcal types. J. exp. Med.97, 137–158 (1944).

    Google Scholar 

  16. Mosler, U. (Compiler): The annotated bibliography of research on planarians, part VIII. Worm Runner's Digest8, No 1, 48–63 (1966).

    Google Scholar 

  17. Quarton, G. C.: The enhancement of learning by drugs and the transfer of learning by macromolecules. In: The neurosciences — a study program (G. C. Quarton, T. Melnechuck, andF. O. Schmitt, eds.). New York: Rockefeller University Press (in press).

  18. Babich, F. R., A. L. Jacobson, S. Bubash, andA. Jacobson: Transfer of a response to naive rats by injection of ribonucleic acid extracted from trained rats. Science149, 656–657 (1965).

    Google Scholar 

  19. Fjerdingstad, E. J., T. Nissen, andH. H. Røigaard-Petersen: Effect of ribonucleic acid (RNA) extracted from the brain of trained animals on learning in rats. Scand. J. Physchol.6, 1–6 (1965).

    Google Scholar 

  20. Albert, D. J.: Memory in mammals: evidence for a system involving nuclear ribonucleic acid. Neuropsychologia4, 79–92 (1966).

    Google Scholar 

  21. Rosenblatt, F., J. T. Farrow, andW. F. Herblin: Transfer of conditioned responses from trained rats to untrained rats by means of a brain extract. Nature (Lond.)209, No 5018, 46–48 (1966).

    Google Scholar 

  22. Ungar, G., andM. Cohen: Transfer of morphine tolerance by material extracted from brain. Intern. J. Neuropharmacology5, 183–192 (1966).

    Google Scholar 

  23. Byrne, W. L., D. Samuel, E. L. Bennett et al.: Memory transfer. Science153, 658–659 (1966).

    Google Scholar 

  24. Jerne, N. K.: Antibodies and learning: selection versus instruction. In: The neurosciences — a study program, op. cit.

  25. Eigen, M.: Molekularkinetik biologischer Informations-übertragung. Gesellschaft Deutscher Naturforscher und Ärzte, 104. Versammlung Wien, 28. September 1966.

  26. De Robertis, E. D. P.: Histophysiology of synapses and neuro-secretion. London: Pergamon Press; New York: Macmillan & Co. 1964.

    Google Scholar 

  27. Taxi, J.: Contribution à l'Étude des Connexions des Neurones moteurs du Systéme nerveux autonome. Paris: Masson & Cie. 1965.

    Google Scholar 

  28. Hama, K.: Some observations on the fine structure of the synapse. In: 1st International Symposium for Cellular Chemistry, Ohtsu, Japan. Intracellular membranous structure (S. Seno andE. V. Cowdry, eds.), p. 539–548. Okayamai: Society for Cell Biology 1963.

    Google Scholar 

  29. Gray, E. G.: Electron microscopy of the cell surface. Endeavour23, No 89, 61–65 (1964).

    Google Scholar 

  30. Robertson, J. D.: The synapse: morphological and chemical correlates of function. In: Neurosciences Research Symposium Summaries, Vol. 1 (F. O. Schmitt andT. Melnechuk, eds.), p. 463–541. Cambridge: M.I.T. Press 1966.

    Google Scholar 

  31. Bornstein, M. B., andS. M. Crain: Functional studies of cultured brain tissues as related to “demyelinative disorders.” Science148, No 3674, 1242–1244 (1965).

    Google Scholar 

  32. Crain, S. M., andM. B. Bornstein:Cf.: Living synapse. In:J. D. Robertson (Ref. No 30), loc. cit. p. 470–476, 1966.

    Google Scholar 

  33. Morrell, F.: Electrical signs of sensory coding. In: The neurosciences — a study program, op. cit.

  34. Huneeus-Cox, F., H. L. Fernandez, andB. H. Smith: Effects of redox and sulfhydryl reagents on the bioelectrical properties of the giant axon of the squid. Biophys. J.6, 675–689 (1966).

    Google Scholar 

  35. Rojas, E., andM. Luxoro: Micro-injection of trypsin into axons of squid. Nature (Lond.)199, 78–79 (1963).

    Google Scholar 

  36. Rojas, E.: Membrane potentials, resistance, and ion permeability in squid giant axons injected or perfused with proteases. Proc. nat. Acad. Sci. (Wash.)53, 306–311 (1965).

    Google Scholar 

  37. Schmitt, F. O.: Molecular and ultrastructural correlates of function in neurons, neuronal nets, and the brain. Naturwissenschaften53, No 3, 71–79 (1966).

    Google Scholar 

  38. Schmitt, F. O., andP. F. Davison: Role of protein in neural function. Neurosci. Res. Progr. Bull.3, No 6, 55–76 (1965).

    Google Scholar 

  39. Orrego, F., andF. Lipmann: Protein synthesis in brain slices: its inhibition by electric stimulation and acidic amino acids. J. biol. Chem.242, 665–671 (1967).

    Google Scholar 

  40. Curtis, D. R., andJ. C. Watkins: Acidic amino acids with strong excitatory actions on mammalian neurones. J. Physiol. (Lond.)166, 1–14 (1963).

    Google Scholar 

  41. Krnjevió, K.: Chemical transmission in the central nervous system. Endeavour25, No 94, 8–12 (1966).

    Google Scholar 

  42. John, E. R.: Electrophysiological studies of conditioning. In: The neurosciences — a study program, op. cit.

  43. Adey, W. R., R. T. Kado, andD. O. Walter: Impedance characteristics of cortical and subcortical structures: evaluation of regional specificity in hypercapnia and hypothermia. Exp. Neurol.11, 190–216 (1965).

    Google Scholar 

  44. Adey, W. R.: Intrinsic organization of cerebral tissue in alerting, orienting, and discriminatory responses. In: The neurosciences — a study program, op. cit.

  45. Rowland, V., andM. Goldstone: Appetitively conditioned and drive-related bioelectric baseline shift in cat cortex. Electroenceph. clin. Neurophysiol.15, 474–485 (1963).

    Google Scholar 

  46. Rowland, V.: Steady-potential phenomena of cortex. In: The neurosciences — a study program, op. cit.

Download references

Author information

Authors and Affiliations

  1. Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts

    Francis O. Schmitt

  2. Neurosciences Research Program, Brookline, Massachuseets

    Francis O. Schmitt

Authors
  1. Francis O. Schmitt
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Vortrag auf der 104. Versammlung der Gesellschaft Deutscher Naturfoscher und Ärzte, Wien 1966.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schmitt, F.O. Makromolekulare Datenverarbeitung im Zentralnervensystem. Klin Wochenschr 45, 863–868 (1967). https://doi.org/10.1007/BF01745682

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01745682

Search

Navigation