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Digital Flashing Tomosynthesis (DFTS) — A technique for three-dimensional coronary angiography

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Abstract

Digital Flashing Tomosynthesis (DFTS) represents a technique for three-dimensional (3D) coronary angiography. Four ECG-gated simultaneously flashed X-ray tubes generate a multiperspective digital substraction image as DFTS multiangiogram for 3D reconstruction and visualization. Computerized morphologic and morphometric quantitative analysis can be performed including videodensitometry.

Postmortem coronary angiography of 30 human hearts with suspected coronary artery disease was performed by 35-mm cine technique and by DFTS. The results of angiographic measurements in 50 stenotic arterial segments were compared with the histologic reference and show excellent regression results with correlation coefficients of more than 0.95 (p≲-0.0001). No significant differences in standard errors of estimates between the techniques were found. DFTS yields an accuracy in depiction of the coronary arteries and angiographic estimation of arterial lumen equivalent to 35-mm cineangiography. DFTS images can be directly used for visual interpretation and for computerized morphologic and morphometric quantitative analysis. DFTS technology reduces the amount of radiation exposure, the amount of contrast medium, and the time of the procedure. DFTS offers the possibility to obtain 3D images of the coronary artery tree.

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Authors and Affiliations

  1. Department of Cardiology, University Hospital Eppendorf, Martinistraße 52, D-2000, Hamburg 20

    G. M. Stiel, L. S. G. Stiel, K. Donath, J. Schofer, P. Haaker, E. Klotz, R. Koppe, R. Linde & D. G. Mathey

  2. Institute of Pathology, University Hospital Eppendorf, Martinistraße 52, D-2000, Hamburg 20

    K. Donath & E. Klotz

  3. Philips GmbH Forschungslaboratorium Hamburg, Vogt-Kölln-Straße 30, D-2000, Hamburg 54, FRG

    P. Haaker, R. Koppe & R. Linde

Authors
  1. G. M. Stiel
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  2. L. S. G. Stiel
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  3. K. Donath
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  4. J. Schofer
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  5. P. Haaker
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  6. E. Klotz
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  7. R. Koppe
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  8. R. Linde
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  9. D. G. Mathey
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Stiel, G.M., Stiel, L.S.G., Donath, K. et al. Digital Flashing Tomosynthesis (DFTS) — A technique for three-dimensional coronary angiography. Int J Cardiac Imag 5, 53–61 (1989). https://doi.org/10.1007/BF01745232

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  • DOI: https://doi.org/10.1007/BF01745232

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