Summary
A Japan-Korea cooperative survey on Takayasu arteritis has shown some differences in the features between Japanese and Korean patients with this disease. In angiographic findings, Japanese patients more frequently had lesions at the aortic arch and/or its branches (58% of 75 cases), while, in Korean patients, the abdominal aorta is the site of relatively frequent lesions (30% of 112 cases). Higher occurrence ofHLA-Bw52 was found in Japanese patients in comparison with Korean patients (46% vs 15%). The presence ofHLA-Bw52, however, might have a close association with Takayasu arteritis in Korea as well as in Japan. The complications in 126 Japanese and 88 Korean patients were also compared. The complications occurring with higher frequency in Japanese patients were aortic regurgitation, ischemic heart disease, and visual disturbances, while, in Korean patients, the more frequent complications were renovascular hypertension as well as hypertension of some other etiology.
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Yajima M, Namba E, Kakuta T, Nishizaki M, Oniki T, Numano F (1989) Echocardiographic studies of aortic regurgitation in Takayasu arteritis. J Cardiovasc Technol 8:223–230
Nasu T (1982) Takayasu's truncoarteritis. Acta Pathol Ophthalmol Jpn 32 (Suppl. 1):117–131
Takayasu M (1908) Case with unusual changes of the central vessels in the retina. Acta Soc Ophthalmol Jpn 12:554
Luppi-Herrera E, Torres GS, Marcus-Hamer J, Mispireta J, Horwitz S, Vera JE (1977) Takayasu arteritis clinical study of 107 cases. Am Heart J 93:94–103
Akasaka T, Yoshikawa J, Yoshida K, Okumachi F, Koizumi K, Shiratori K, Takano S, Shakudo M, Kato H (1987) Age-related valvular regurgitation. A study by pulsed Doppler echocardiography. Circulation 76:262–265
Committee report (1968) Clinical and pathological studies of Takayasu disease. A report by the Japanese Ministry of Welfare
Committee report (1975) Clinical and pathological studies of Takayasu disease. A report by the Japanese Ministry of Welfare
Numano F, Isohisa I, Kishi Y, Arita M, Maezawa H (1978) Takayasu disease in twin sisters — possible genetic factors. Circulation 58:173–177
Deutch V, Wexler L, Deutsch H (1974) Takayasu's arteritis. An angiographic study with remarks on ethnic distribution in Israel. Am J Roentgenol. 122:12
Numano F, Isohisa I, Maezawa H, Juji T (1979) HLA antigens in Takayasu's disease. Am Heart J 98:153–159
Isohisa I, Numano F, Maezawa H, Sasazuki T (1978)HLA-Bw52 in Takayasu disease. Tissue Antigens 12:246–248
Isohisa I, Numano F, Mezawa H, Sasazuki T (1982) Hereditary factors in Takayasu disease. Angiology 33:98–104
Numano F, Ota N, Sasazuki T (1982) HLA and clinical manifestation in Takayasu disease. Jpn Circulation J 46:184–189
Morooka S, Takeda T, Saito Y, Nonaka Y, Murao S (1981) Dilatation of the aortic valve portion on aortitis syndrome. Angiographic evaluation of 70 patients. Jpn Heart J 22:517
Turkoglu C, Yajima M, Numano F (1982) Echocardiography of the aortic root in patients with Takayasu's disease in the presence or absence of aortic regurgitation. J Cardiovasc Ultrasonogr 1:147–150
Ueda H, Sugiura M, Ito I, Saito Y, Morooka S (1967) Aortic insufficiency associated with aortitis syndrome. Jpn Heart J 8:107–120
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Yajima, M., Moriwaki, R., Numano, F. et al. Comparative studies between Japanese and Korean patients: Comparison of the findings of angiography,HLA-Bw52, and clinical manifestations. Heart Vessels 7 (Suppl 1), 102–105 (1992). https://doi.org/10.1007/BF01744553
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DOI: https://doi.org/10.1007/BF01744553