The future role of neurosurgery in the care of cerebral tumors
- 22 Downloads
Diagnostic methods to discover a brain tumor and surgical techniques to remove it are steadily advancing. Most well-demarcated tumors can be removed by operation alone. Malignant, invasive tumors, however, will continue to offer a difficult and serious problem except when they are found while still very small in size, by elaborate diagnostic tools and except when they are conveniently located. For those tumors, surgery alone is not enough. Extermination of tumor cells by surgery, radiotherapy, chemotherapy, immunotherapy, etc., or combinations of these has achieved some results but with considerable limitations. We must search for the ways of peaceful coexistence with tumor cells, i.e., living with the tumor cells which are kept non-dividing and nonmetastasizing by some means. Recent developments in oncology, such as discovery of c-onc genes, various growth factors, etc., give us some hope in the researches in this direction.
KeywordsBrain tumor growth factors labelling index oncogenes
Unable to display preview. Download preview PDF.
- Bishop, J. M.: Oncogenes. Sci. Am. 246, No. 3 (1982) 68–78Google Scholar
- Committee of Brain Tumor Registry in Japan: Brain tumor registry in Japan Vol. 5, National Cancer Center, Tokyo 1984Google Scholar
- Cutler, S. J.: Computation of survival rate. NCI Monograph 15 (1964) 381–385Google Scholar
- Nagashima, T., S. J. DeArmond, J. Murovic, et al.: Immunocytochemical demonstration of S-phase cells by anti-bromodeoxyuridine monoclonal antibody in human brain tumors. Acta Neuropathol. (in press)Google Scholar
- Nagashima, T., T., Hoshino: A review of cell kinetic studies on brain tumors with a special reference to anti-bromodeoxyuridine monoclonal antibody method. Neurol. Surg. 12 (1984) 1007–1018 (Japan)Google Scholar
- Sano, K.: Chemo-radiotherapy of malignant brain tumors. In: Carrea, R.: Proc. 6th Internat. Congr. Neurol. Surg. pp. 79–87. Excerpta Medica, Amsterdam—Oxford 1977Google Scholar