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Changing biclonal gammopathy due to different lymphocyte clones in acquired immunodeficiency syndrome with kaposi's sarcoma

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Summary

We report the first case of acquired immunodeficiency-syndrome (AIDS) with Kaposi's sarcoma which at the same time has also a changing biclonal gammopathy (initial: double IgG-paraproteinaemia, lateron IgA-IgG Double-paraproteinaemia) due to different lymphocyte clones. The relationship of a B-cell neoplasia to a concurrent disease of T-cells is discussed.

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Abbreviations

AIDS:

Acquired Immunodeficiency Syndrome

CDC:

Centers for Disease Control

CMV-VCA:

Cytomegalo Virus — Virus Capsid Antigen

DNA:

Desoxyribonucleic Acid

EBV:

Epstein Barr Virus

EBV-VCA:

Epstein Barr Virus — Virus Capsid Antigen

EBV-EA:

Epstein Barr Virus — Early Antigen

EBNA:

Epstein Barr Nuclear Antigen

ELISA:

Enzyme Linked Immunosorbent Assay

ESR:

Erythrocyte Sedimentation Rate

Hb:

Hemoglobin

HTLV:

Human T-Lymphotropic Retrovirus

NT:

Not tested

OKT 4:

T-Helper/Inducer Cells

OKT 8:

T-Suppressor/Cytotoxic Cells

PHA:

Phytohemagglutinin

PWM:

Pokeweed Mitogen

WBC:

White Blood Cells

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Authors and Affiliations

  1. Medizinische Poliklinik der Universität München, Germany

    H. Piechowiak, R. Hehlmann, F. D. Goebel, M. M. Kochen & G. Kreeb

  2. Max-von-Pettenkofer-Institut der Universität München, Germany

    J. Abb

  3. Abteilung für Pathologie, Gesellschaft für Strahlen- und Umweltforschung, Neuherberg

    V. Erfle

Authors
  1. H. Piechowiak
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  2. R. Hehlmann
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  3. J. Abb
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  4. V. Erfle
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  5. F. D. Goebel
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  6. M. M. Kochen
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  7. G. Kreeb
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Piechowiak, H., Hehlmann, R., Abb, J. et al. Changing biclonal gammopathy due to different lymphocyte clones in acquired immunodeficiency syndrome with kaposi's sarcoma. Klin Wochenschr 63, 1083–1086 (1985). https://doi.org/10.1007/BF01739678

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  • DOI: https://doi.org/10.1007/BF01739678

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