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Shunt nephritis associated withPropionibacterium acnes

Shuntnephritis mit Propionibacterium acnes

Summary

Membranoproliferative glomerulonephritis was observed in a 22-year-old male patient in whom a ventriculoatrial shunt and a ventricular catheter were implanted after he was diagnosed in September 1989 with a cerebral cyst.Propionibacterium acnes infection of a central nervous system shunt was diagnosed. The venticuloatrial shunt was removed (the catheter had become embedded in tissue and was left in place) and the patient was treated with cefotaxime (3×2 g) for 14 days. Renal function improved, but recovery was not complete.

Zusammenfassung

Bei einem 22jährigen Patienten, der im September 1989 einen ventrikuloatrialen Shunt und einen Ventrikelkatheter zur Therapie einer zerebralen Zyste implantiert erhielt, wurde eine membranoproliferative Glomerulonephritits in Assoziation mit einer Shuntinfektion durchPropionibacterium acnes diagnostiziert. Obgleich Infektionen von zentralnervösen Shunts nichts Ungewöhnliches darstellen, ist die Entwicklung einer Glomerulonephritis eine Seltenheit. Vermutlich ist die Shuntnephritis die Folge einer Immunkomplexantwort und der Ablagerung von Immunkomplexen in der Niere. Nach der nur unvollständigen Entfernung des Shunts aufgrund technischer Probleme und zusätzlicher Gabe von 3 × 2 g Cefotaxim für 14 Tage verbesserte sich die Nierenfunktion, jedoch trat keine komplette Remission ein.

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Setz, U., Frank, U., Anding, K. et al. Shunt nephritis associated withPropionibacterium acnes . Infection 22, 99–101 (1994). https://doi.org/10.1007/BF01739014

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Keywords

  • Catheter
  • Renal Function
  • Family Medicine
  • Acne
  • Nephritis