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Increased bone metabolism in a patient undergoing long-term rhG-CSF treatment for idiopathic acquired neutropenia

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Summary

Recombinant human granulocyte colony-stimulating factor (rhG-CSF) has been used mainly for treatment of chemotherapy-induced neutropenia. The reported side effects were of minor importance. We describe a case of long-term treatment with rhG-CSF, in which we observed enhanced bone remodeling.

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Authors and Affiliations

  1. Central Hematology Laboratory, University of Bern, Inselspital, CH-3010, Bern, Switzerland

    U. J. Woermann & A. Tobler

  2. Institute of Pathophysiology, University of Bern, Murtenstrasse 35, CH-3010, Bern, Switzerland

    R. Schenk

  3. Institute of Pathology, University of Bern, Murtenstrasse 33, CH-3010, Bern, Switzerland

    A. Zimmermann

Authors
  1. U. J. Woermann
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  2. R. Schenk
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  3. A. Zimmermann
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  4. A. Tobler
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Woermann, U.J., Schenk, R., Zimmermann, A. et al. Increased bone metabolism in a patient undergoing long-term rhG-CSF treatment for idiopathic acquired neutropenia. Ann Hematol 66, 267–268 (1993). https://doi.org/10.1007/BF01738479

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  • DOI: https://doi.org/10.1007/BF01738479

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