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Distribution of non-telomeric sites of the (TTAGGG)n telomeric sequence in vertebrate chromosomes

Chromosoma volume 99, pages 3–10 (1990)Cite this article

Abstract

The intrachromosomal distribution of non-telomeric sites of the (TTAGGG)n telomeric repeat was determined for 100 vertebrate species. The most common non-telomeric location of this sequence was in the pericentric regions of chromosomes. A variety of species showed relatively large amounts of this sequence present within regions of constitutive heterochromatin. We discuss possible relationships between the non-telomeric distribution of the (TTAGGG)n sequence and the process of karyotype evolution, during which these sites may provide potential new telomeres.

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Affiliations

  1. Genetics Group, Los Alamos National Laboratory, 87545, Los Alamos, NM, USA

    Julianne Meyne & Robert K. Moyzis

  2. Department of Biological Sciences, Texas Tech University, Lubbock, TX, USA

    Robert J. Baker

  3. Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ, USA

    Holly H. Hobart & Oscar G. Ward

  4. Department of Cell Biology, The University of Texas M.D. Anderson Cancer Center, 77030, Houston, TX, USA

    T. C. Hsu

  5. Center for Reproduction of Endangered Species, The Zoological Society of San Diego, San Diego, CA, USA

    Oliver A. Ryder

  6. Department of Pediatrics, School of Medicine, East Carolina University, Greenville, NC, USA

    John E. Wiley

  7. Department of Pathology, Dartmouth Medical School, Hanover, NH, USA

    Doris H. Wurster-Hill

  8. Department of Biology, University of New Mexico, Albuquerque, NM, USA

    Terry L. Yates

Authors
  1. Julianne Meyne
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  2. Robert J. Baker
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  3. Holly H. Hobart
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  4. T. C. Hsu
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  5. Oliver A. Ryder
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  6. Oscar G. Ward
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  7. John E. Wiley
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  8. Doris H. Wurster-Hill
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  9. Terry L. Yates
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  10. Robert K. Moyzis
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Meyne, J., Baker, R.J., Hobart, H.H. et al. Distribution of non-telomeric sites of the (TTAGGG)n telomeric sequence in vertebrate chromosomes. Chromosoma 99, 3–10 (1990). https://doi.org/10.1007/BF01737283

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  • DOI: https://doi.org/10.1007/BF01737283

Keywords

  • Developmental Biology
  • Vertebrate Species
  • Telomeric Repeat
  • Pericentric Region
  • Telomeric Sequence