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LDH-Isoenzyme und Schwangerschaft

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Zusammenfassung

Im menschlichen Uterusmuskel verschiebt sich das Isoenzymmuster der LDH im Verlauf der Schwangerschaft. Als Ursache kommt eine Änderung im Enzymgehalt der Zelle in Frage oder aber das vermehrte Wachstum einer Zellsorte im nachweislich heterogenen Uterusmuskel. Durch Untersuchung der LDH in Myomknoten schwangerer Uteri konnte bewiesen werden, daß die Enzyme in der Zelle verändert werden.

Summary

In human myometrium the proportions of LDH-Isoenzymes are changed during pregnancy. This may be caused by either an alteration of enzymes in the cell or an additional growth of one cell-type in the heterogenous myometrium. Examination of leiomyomas in pregnant uteri demonstrate LDH within the cell to be changed.

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Literatur

  1. Geyer, H.: Isoenzyme der Lactatdehydrogenase im Uterusmuskel. Klin. Wschr.46, 443 (1968).

    Google Scholar 

  2. Geyer, H.: LDH-Isoenzyme in Tumoren des menschlichen Uterus. Klin. Wschr.46, 389 (1968).

    Google Scholar 

  3. Goodfriend, T. L., D. M. Sokol, andN. O. Kaplan: Control of synthesis of LDH's. J. molec. Biol.15, 18 (1966).

    Google Scholar 

  4. Jaeger, J.: Variations in the morphological substrate of the smooth muscle cells of the pregnant and non-pregnant human uterus. In: Uterine contractility. Symposium in Würzburg 1964. Bibl. gynaec., Fasc.42, 13–28 (1966).

    Google Scholar 

  5. Kar, N. C., andC. M. Pearson: Developmental changes and heterogeneity of lactic- and malic dehydrogenases of human skeletal muscles and other organs. Proc. nat. Acad. Sci. (Wash.)50, 995 (1963).

    Google Scholar 

  6. Lindner, D., andS. M. Gartler: Glucose-6-phosphate dehydrogenase mosaicism: utilization as a cell marker in the study of leiomyomas. Science150, 67 (1965).

    Google Scholar 

  7. Richterich, P., P. Schafroth, andH. Aebi: A study of lactic dehydrogenase isoenzyme pattern of human tissues by adsorption-elution on Sephadex-DEAE. Clin. chim. Acta8, 178 (1963).

    Google Scholar 

  8. Wijhe, M. van, M. C. Blanchaer, andS. St. George-Stubbs: The distribution of lactate dehydrogenase isoenzymes in human skeletal muscle fibers. J. Histochem. Cytochem.12, 608 (1964).

    Google Scholar 

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Authors and Affiliations

  1. Universitäts-Frauenklinik Freiburg i. Br., Germany

    H. Geyer

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  1. H. Geyer
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Geyer, H. LDH-Isoenzyme und Schwangerschaft. Klin Wochenschr 46, 446–447 (1968). https://doi.org/10.1007/BF01736938

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  • DOI: https://doi.org/10.1007/BF01736938

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