Skip to main content
Log in

A model for the origin of life

  • Published:
Journal of Molecular Evolution Aims and scope Submit manuscript

Summary

A simple statistical model is constructed, describing the transition from disorder to order in a population of mutually catalytic molecules undergoing random mutations. The consequences of the model are calculated, and its possible relevance to the problem of the origin of life is discussed. The main conclusion of the analysis is that the model allows populations of several thousand molecular units to make the transition from disorder to order with reasonable probability.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Biebricher CK, Eigen M, Luce R (1981) Kinetic Analysis of Template-instructed and de novo RNA Synthesis by Q β Replicase. J Mol Biol 148:391–410

    Google Scholar 

  • Bresch C, Niesert U, Harnasch D (1980) Hypercycles, Parasites and Packages. J Theor Biol 85:399–405

    Google Scholar 

  • Crick FHC (1957) On Protein Synthesis. Symp Soc Exp Biol 12:138–163

    Google Scholar 

  • Fisher RA (1930) The Genetical Theory of Natural Selection, (New York, Dover Publications reprint, 1958) Chapter 4

  • Kimura M (1970) Stochastic Processes in Population Genetics, In: Kojima KI (ed) Mathematical Topics in Population Genetics. Springer, Berlin Heidelberg New York, p 178–209

    Google Scholar 

  • Kirkwood TBL (1980) Error Propagation in Intracellular Transfer. J Theor Biol 82:363–382

    Google Scholar 

  • Kuhn H, Waser J (1981) Molecular Self-Organization and the Origin of Life. Angew Chem Int Ed Engl 20:500–520

    Google Scholar 

  • Lohrmann R, Bridson PK, Orgel LE (1980) Efficient Metal-Ion Catalyzed Template-directed Oligonucleotide Synthesis. Science 208:1464–1465

    Google Scholar 

  • Miller SM, Orgel LE (1974) The Origins of Life on the Earth. Prentice-Hall, Englewood Cliffs NJ

    Google Scholar 

  • Niesert U, Harnasch D, Bresch C (1981) Origin of Life between Scylla and Charybdis. J Mol Evol 17:348–353

    Google Scholar 

  • Weiss A (1981) Replication and Evolution in Inorganic Systems. Angew Chem Int Ed Engl 20:850–860

    Google Scholar 

  • Wright S (1931) Evolution in Mendelian Populations. Genetics 10:97–159

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Dyson, F.J. A model for the origin of life. J Mol Evol 18, 344–350 (1982). https://doi.org/10.1007/BF01733901

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01733901

Key words

Navigation