Klinische Wochenschrift

, Volume 63, Issue 13, pp 583–589 | Cite as

Histiozytosis X

Verlaufsbeobachtung über 20 Jahre bei einem Patienten mit Morbus Hand-Schüller-Christian
  • R. Böhmer
  • W. Saeger
  • I. Jend-Rossmann
Originalien

Abkürzungen

ACTH

Adrenocorticotropes Hormon

ADH

Antidiuretisches Hormon

BSG

Blutkörperchensenkungsgeschwindigkeit

PA

Pulmonalarteriendruck

PC

pulmonaler Capillardruck

Histiocytosis X — A twenty-year observation of a patient with morbus hand-schüller-christian

Summary

Since 1963 we have observed a patient with Hand-Schüller-Christian disease with involvement of the skeleton, skin and hypophysis/hypothalamus with diabetes insipidus. The diabetes insipidus was successfully treated initially with chlorpropamid and later with carbamazepin.

Alterations of the lung parenchyma were seen radiologically in 1966, and two years later the patient complained of exertional dyspnea. The lung disease was progressive with the deterioration of lung function despite corticosteroid and D-penicillamine treatment. The patient now has marked dyspnea even at rest. The osteolytic lesions have not changed in recent years.

Key words

Histiocytosis X Diabetes insipidus Osteolytic lesions Pulmonary fibrosis 

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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • R. Böhmer
    • 1
    • 2
  • W. Saeger
    • 1
    • 2
  • I. Jend-Rossmann
    • 1
    • 2
  1. 1.1. Medizinische Abteilung und Abteilung für Pathologie des Marienkrankenhauses HamburgGermany
  2. 2.Nordwestdeutsche Kieferklinik Universitätskrankenhaus EppendorfHamburg

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