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Inadequacy of prebiotic synthesis as origin of proteinous amino acids

Journal of Molecular Evolution volume 13, pages 115–125 (1979)Cite this article

Summary

The production of some nonproteinous, and lack of production of other proteinous, amino acids in model prebiotic synthesis, along with the instability of glutamine and asparagine, suggest that not all of the 20 presentday proteinous amino acids gained entry into proteins directly from the primordial soup. Instead, a process of active co-evolution of the genetic code and its constituent amino acids would have to precede the final selection of these proteinous amino acids.

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Authors and Affiliations

  1. Department of Biochemistry, University of Toronto, M5S 1A8, Toronto, Canada

    J. Tze-Fei Wong & Patricia M. Bronskill

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  1. J. Tze-Fei Wong
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  2. Patricia M. Bronskill
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Wong, J.TF., Bronskill, P.M. Inadequacy of prebiotic synthesis as origin of proteinous amino acids. J Mol Evol 13, 115–125 (1979). https://doi.org/10.1007/BF01732867

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  • DOI: https://doi.org/10.1007/BF01732867

Keywords

  • Glutamine
  • Asparagine
  • Genetic Code
  • Proteinous Amino Acid
  • Final Selection