Summary
An automatic perfusion system for segmental measurements of intestinal absorption is described. This makes use of the triple-lumen tube according to Ingelfinger and coworkers. Its application for diagnostic procedures in routine gastroenterology is shown. The reliability of the data obtained is demonstrated by repeated measurements in the same patient. The advantage of this method is discussed in comparison with the techniques hitherto used.
Zusammenfassung
Es wird über eine neu entwickelte automatisierte Methode der segmentalen Dünndarmperfusion berichtet, die ein dreilumiges Sondensystem (Ingelfinger et al.) verwendet. Durch die erreichte Vereinfachung der Technik erscheint es möglich, diese Methode jetzt auch in Kliniken, vor allem in der speziellen gastroenterologischen Diagnostik einzusetzen.
An Hand von Mehrfachmessungen am gleichen Patienten wird die Reproduzierbarkeit der Ergebnisse und die Validität der Methodik herausgestellt und ihr Vorteil gegenüber bisher gebräuchlichen Verfahren diskutiert.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literatur
Cooper, H., Levitan, R., Fordtran, J. S., Ingelfinger, F. J.: A method for studying absorption of water and solute from the human small intestine. Gastroenterology50, 1–7 (1966).
Fordtran, J. S., Levitan, R., Bikerman, V., Burrows, B. A.: The kinetics of water absorption in the human intestine. Trans. Ass. Amer. Phycns 195–205 (1961).
—— Soergel, K. H., Ingelfinger, F. J.: Intestinal absorption of D-xylose in man. New Engl. J. Med.267, 274 (1962).
Fordran, J. S.: Marker perfusion techniques. Gastroenterology51, 1089–1093 (1966).
—— Segmental perfusion techniques. Gastroenterology56, 987–989 (1969).
—— In: Handbook of physiology, sect. 6: Alimentary canal, vol. III. Washington D. C.: Amer. Physiol. Society 1968.
Gray, G. M., Ingelfinger, F. J.: Intestinal absorption of sucrose in man: Interrelation of hydrolysis and monosaccharide product absorption. J. clin. Invest.45, 3 (1966).
Haemmerli, U. P., Amman, R.: Malabsorption. Moderne Untersuchungsmethoden und Differentialdiagnose. Schweiz. Med. Wschr.43, 1517 (1963).
Hydén, S.: A turbidometric method for the determination of higher polyethylene glycols in biologic materials. K. Lantbr. Högsk. Annlr.22, 139–145 (1955).
Kalser, M. H.: In: Gastroenterology (H. L. Bockus), vol. II: Malabsorption syndromes, part III: Tests of malabsorption syndrome, p. 492–509, 1964.
Schedl, H. P., Clifton, J. A.: Kinetics of intestinal absorption in man: normal subjects and patients with sprue (abstract). J. clin. Invest.40, 1079 (1961).
Sladen, G. E., Dawson, A. M.: An evaluation of perfusion techniques in the study of water and electrolyte absorption in man: the problem of endogenous secretions. Gut9, 530 (1968).
—— Perfusion studies in relation to intestinal absorption. Gut9, 624–628 (1969).
—— Dawson, A. M.: Further studies on the perfusion method for measuring intestinal absorption in man: the effect of a proximal occlusive ballon and a mixing segment. Gut11, 947–954 (1970).
Soergel, K. H.: An evaluation of perfusion techniques in the study of water and electrolyte absorption in man: the problem of endogenous secretions. Gut10, 601 (1969).
Whalen, G. E., Harris, J. A., Geenen, J. E., Soergel, K. H.: Sodium and water absorption from the human small intestine. The accuracy of the perfusion method. Gastroenterology51, 975–984 (1966).
Author information
Authors and Affiliations
Additional information
Mit Unterstützung durch die Deutsche Forschungsgemeinschaft.
Rights and permissions
About this article
Cite this article
Bloch, R., Menge, H., Lorenz-Meyer, H. et al. Automatisierte segmentale Dünndarmperfusion. Klin Wochenschr 49, 1218–1222 (1971). https://doi.org/10.1007/BF01732730
Issue Date:
DOI: https://doi.org/10.1007/BF01732730