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Journal of Molecular Evolution

, Volume 6, Issue 3, pp 233–236 | Cite as

Conjugate paralogous crossing-over as an explanation for the tyrosine/phenylalanine polymorphism at position 24 in bothα-chains of horse hemoglobin

  • J. J. Beintema
Letter to the Editor

Summary

Horse hemoglobin contains two α-chains which differ in the presence of lysine or glutamine at position 60. These two chains are the result of a recent gene duplication. Both chains show an identical tyrosine/phenylalanine polymorphism at position 24. The origin of both polymorphisms is explained by conjugate paralogous crossing-over.

Key words

Crossing-Over Paralogy Polymorphism Horse Hemoglobin 

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References

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Copyright information

© Springer-Verlag 1975

Authors and Affiliations

  • J. J. Beintema
    • 1
  1. 1.Biochemisch LaboratoriumRijksuniversiteitZernikelaanThe Netherlands

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