Abstract
A polymorphism for thyroxine-binding prealbumin (TBPA) is investigated in regards to mode of inheritance as well as distribution within eight species of macaques from known geographic areas. It is found that an electrophoretically slow variant seems to be due to a codominant allele present in six of the species tested.
While the slow form has a frequency of less than 30% in most other populations tested, it is fixed at 100% in the Japanese macaques (M. fuscata). The locus is inHardy-Weinberg equilibrium in all populations however. Since TBPA is intimately related to thyroxine levels in the blood the polymorphism may be an adaptation to cold environments.
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Weiss, M.L., Goodman, M., Prychodko, W. et al. Species and geographic distribution patterns of the macaque prealbumin polymorphism. Primates 12, 75–80 (1971). https://doi.org/10.1007/BF01730383
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DOI: https://doi.org/10.1007/BF01730383