Summary
We report a typical case of post-transfusion purpura (PTP) due to anti-PlAl in a 65-year-old woman. Serological studies were carried out using flow cytometry (FCM). The patient also developed red cell alloantibodies that produced a delayed hemolytic transfusion reaction (DHTR) and broad HLA antibodies. Treatment with high-dose intravenous IgG (HDIgG; a first-generation preparation) was ineffective, but a course of steroids resulted in a rapid increase in the the platelet count.
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Puig, N., Sayas, M.J., Montoro, J.A. et al. Post-transfusion purpura as the main manifestation of a trilineal transfusion reaction, responsive to steroids: flow-cytometric investigation of granulocyte and platelet antibodies. Ann Hematol 62, 232–234 (1991). https://doi.org/10.1007/BF01729839
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DOI: https://doi.org/10.1007/BF01729839