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37. Praktische Bedeutung gastrointestinaler Hormone in der Chirurgie (Gastrinome, Antrumrest)

Clinical aspects of gastrointestinal hormones in surgery

  • C. Chirurgie der Erkrankungen endokriner Organe
  • b) Pankereas und gastrointestinale Hormone
  • Published:
Langenbecks Archiv für Chirurgie Aims and scope Submit manuscript

Summary

The development of radioimmunoassays and the detection of numerous polypeptides in the GI-tract mucosa have induced extensive research. In surgery GI hormones are of clinical importance in diagnostic procedures and in the treatment of paralytic ileus (CCK). GI hormones play a role in the pathogenesis of recurrent ulceration after surgical therapy. GI-hormone producing tumors are responsible for the Zollinger-Ellison syndrome, VernerMorrison syndrome and the glucagonoma syndrome.

Zusammenfassung

Durch die Entwicklung der radioimmunologischen Bestimmungsmethoden und die Entdeckung zahlreicher Polypeptide im Gastrointestinaltrakt sind die gastrointestinalen Hormone Gegenstand zahlreicher Untersuchungen gewesen. Für den Chirurgen sind gastrointestinale Hormone vor allem als Diagnostica sowie in der Behandlung des paralytischen Ileus (CCK) von Bedeutung. Pathogenetisch spielen die GI-Hormone eine Rolle bei der Entstehung von Recidivulcera nach chirurgischer Therapie. GI-Hormon-produzierende Tumoren sind für das Zollinger-Ellison-, das Verner-Morrison- und das Glucagonom-Syndrom verantwortlich.

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Literatur

  1. Becker, H. D.: Methodische Fortschritte in der Funktionsdiagnostik des Magens. Magensekretionsanalyse, intragastrale Titration, Provokationsteste. Z. Gastroenterol.16, 118 (1978)

    Google Scholar 

  2. Becker, H. D., Schafmayer, A., Börger, H. W.: Die Behandlung der Blutung aus akuten Schleimhautldsionen des Magens und Duodenums durch Sekretin. Chirurg50, 87 (1979)

    Google Scholar 

  3. Bloom, S. R., Polak, J. M.: The role of VIP in pancreatic cholera. In: Gastrointestinal hormones. Ed.: Thompson, J. C., p.635. Austin: Univ. Texas Press 1975

    Google Scholar 

  4. Bonfils, S., Mignon, M., Kloeti, G.: Cimetidine treatment in Zollinger-Ellison-syndrome. In: Gastrointestinal hormones and pathology of the digestive system. Eds.: Grossman, M., Speranza, V., Basso, N., Lezoche, E. Ser. Adv. Exp. Med. Biol.106, 111 (1978)

  5. Creutzfeldt, W., Arnold, R., Creutzfeldt, C., Tracke, N. S.: Pathomorphologic, biochemical and diagnostic aspects of gastrinomas. Hum. Pathol.6, 47 (1975)

    Google Scholar 

  6. Deveney, C. W., Deveney, K. S., Way, L. W.: The Zollinger-Ellison-syndrome-23 years later. Ann. Surg.188, 384 (1978)

    Google Scholar 

  7. Gyr, K., Kayassek, L., Meyer, F. D., Stalder, G. A.: Somatostatin and cimetidine in gastroduodenal hemorrhage. Preliminary report. In: Cimetidine. Ed.: Creutzfeldt, W., p.299. Amsterdam: Excerpta Medica 1978

    Google Scholar 

  8. Jaffe, B. M.: The diarrheogenic syndrome: Verner Morrison, WDHA syndrome. In: Surgical endocrinology. Ed.: Friesen, S. R. Philadelphia: Lippincott 1978

    Google Scholar 

  9. Mallinson, C., Bloom, S. R.: The hyperglycemic cutaneous syndrome: Pancreatic glucagonoma. In: Surgical endocrinology. Ed.: Friesen, S. R. Philadelphia: Lippincott 1978

    Google Scholar 

  10. Pearse, A. G. E., Polak, J. M.: Endocrine tumors of neural crest origin: Neurolophomas, syndomas and the apud concept. Med. Biol.52, 3 (1974)

    Google Scholar 

  11. Said, S. J., Faloona, G. R.: Elevated plasma and tissue levels of vasoactive intestinal polypeptide in the watery diarrhea syndrome due to pancreatic, bronchogenic and other tumors. N. Engl. J. Med. 293, 155 (1975)

    Google Scholar 

  12. Stage, J. G., Stadil, F., Fischerman, K.: New aspects in the treatment of the Zollinger-Ellison-syndrome. In: Cimetidine. Ed.: Creutzfeldt, W., p. 137. Amsterdam: Excerpta Medica 1978

    Google Scholar 

  13. Thompson, J. C., Reeder, D. D., Villar, H. V., Fender, H. R.: Natural history and experience with diagnosis and treatment of the Zollinger-Ellison-syndrome. Surg. Gynecol. Obstet.140, 721 (1975)

    Google Scholar 

  14. Unger, R. H., Eisentraut, A. M., Lochner, J. R.: Glucagon producing tumors of the islets of Langerhans. J. Clin. Invest.42, 987 (1963)

    Google Scholar 

  15. Verner, J. V., Morrison, A. B.: Endocrine pancreatic islet cell disease with diarrhea. Arch. Intern. Med.133, 492 (1974)

    Google Scholar 

  16. Zollinger, R. M., Coleman, D. W.: The Zollinger-Ellison-syndrome. In: Surgery of the stomach. Eds.: Nyhus, L. M., Wastell, C., p. 473. Boston: Little, Brown & Comp. 1978

    Google Scholar 

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  1. Klinik für Allgemeinchirurgie der Universität, Robert-Koch-Straße 40, D-3400, Göttingen

    H. D. Becker

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  1. H. D. Becker
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Becker, H.D. 37. Praktische Bedeutung gastrointestinaler Hormone in der Chirurgie (Gastrinome, Antrumrest). Langenbecks Arch Chiv 349, 189–194 (1979). https://doi.org/10.1007/BF01729494

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  • DOI: https://doi.org/10.1007/BF01729494

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