Summary
The effects of a combined exercise and low-fat dientary regimen were studied in 11 patients with angiographically documented coronary heart disease (cholesterol 233 mg/dl, triglycerides 158 mg/dl) and 13 comparable patients (cholesterol 224 mg/dl, triglycerides 174 mg/dl) on usual care. During one year, fasting serum lipoproteins were lowered to “ideal” levels in the intervention group (cholesterol 191 mg/dl, triglycerides 100 mg/dl, LDL-cholesterol 121 mg/dl). There was no change of triglycerides and cholesterol on usual care while LDL-cholesterol rose significantly. Neither regimen had any effect on HDL-cholesterol. Diurnal triglycerides as a presumptive measure of IDL in the intervention group were diminished by 39%. The study demonstrates the feasibility of a diet and exercise regimen to normalize midly elevated plasma lipid levels and thus to possibly affect the course of coronary heart disease without drugs.
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Abbreviations
- Chol:
-
cholesterol
- TG:
-
triglycerides
- HDL:
-
high density lipoproteins
- LDL:
-
low density lipoproteins
- LP(a):
-
lipoprotein (a)
- P/S:
-
polyunsaturated to saturated fatty acid ratio
- Int.:
-
Intervention group
- C:
-
Control group
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Schlierf, G., Schuler, G., Wirth, A. et al. Treatment of coronary heart disease by diet and exercise: Fasting and diurnal lipoproteins. Klin Wochenschr 66, 1103–1109 (1988). https://doi.org/10.1007/BF01727844
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DOI: https://doi.org/10.1007/BF01727844