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Behandlung der Peritonitis während kontinuierlich ambulanter Peritonealdialyse (CAPD) mit Co-Trimoxazol, Cefazolin oder Vancomycin

Treatment of peritonitis during continuous ambulatory peritoneal dialysis (CAPD) by cotrimoxazol, cefazolin and vancomycin

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Summary

Three initial treatment schedules of peritonitis during continuous ambulatory peritoneal dialysis are analysed. In 20 patients 56 peritonitides were treated by co-trimoxazole, 29 episodes in 20 patients by cefazolin, and 29 infections in 22 patients by vancomycin. The efficiency of the treatment modes was comparable. Vancomycin was found to be appropriate in particular because of the resistance characteristics of bacterial isolates.

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Literatur

  1. Altmann P, Butter K, Cunningham J, Drew P, Goodwin F, Marsh F (1984) CAPD peritonitis: 10 or 21 days treatment? (Abstract). Kidney Int 26:544

    Google Scholar 

  2. Ayus JC, Eneas JF, Tong TG, Benowitz NL, Schöfeld PY, Hadley AL, Becker CE, Humphreys MH (1979) Peritoneal clearance and total body elimination of Vancomycin during CAPD. Clin Nephrology 11/3:129–132

    Google Scholar 

  3. Bammatter F, Keusch G, Schiffl H, Koller M, Binswanger U (1980) Kontinuierliche ambulante Peritonealdialyse: Ergebnisse und Komplikationen bei 24 Patienten. Schweiz med Wochenschr 110:689–697

    Google Scholar 

  4. Bennett-Jones DN, Eaton A, Taube D, Wass V, Mawson P, Neild GH, Rudge C, Cameron JS, Williams DG, Ogg CS (1984) A trial of intraperitoneal versus intravenous antibiotics in the treatment of CAPD peritonitis. (Abstract). Kidney Int 26:538

    Google Scholar 

  5. Binswanger U, Bammatter F, Keusch G, Schiffl H, Koller M (1980) Chemical peritonitis during chronic ambulatory peritoneal dialysis? In: Legrain M (Hrsg) Continuous Ambulatory Peritoneal Dialysis. p 238–244, Excerpta Medica, Amsterdam

    Google Scholar 

  6. Binswanger U, Keusch G, Bammatter F, Heule H, Kiss D (1981) Peritonitis during continuous ambulatory peritoneal dialysis: Improving patient defense by type of buffer of dialysate? Nephron 28:300–302

    Google Scholar 

  7. Brauner L, Kahlmeter G, Lindholm T, Simonsen O (1985) Vancomycin and Netilmycin as first line treatment of peritonitis in CAPD-patients. J Antimicrob Chemobl 15:751–758

    Google Scholar 

  8. Cantaluppi A, Castelnova C, Scalamegna A, Guerra L, Graziani G, Ponticelli C (1984) Exit site infections in patients on CAPD (Abstract). Kidney Int 26:545

    Google Scholar 

  9. Corey PN, Steele C (1983) Risk factors associated with time to first infection and time to failure on CAPD. Perit Dial Bull 3 (Suppl):14–17

    Google Scholar 

  10. Diskin CJ, Coplon N, Feldmann C, Vosti K (1983) Antimicrobial activity in continuous ambulatory peritoneal dialysis. Perit Dial Bull 3:150–154

    Google Scholar 

  11. Everett ED (1981) Diagnosis, prevention and treatment of peritonitis. (Abstract). Perit Dial Bull 4 (Suppl):4–7

    Google Scholar 

  12. Fenton S, Wu G, Cattran D, Wadgymar A, Allen AF (1981) Clinical aspects of peritonitis in patients on CAPD. Perit Dial Bull 1 (Suppl):4–7

    Google Scholar 

  13. SSA Fenton (1983) Peritonitis related deaths among CAPD patients. Perit Dial Bull 3 (Suppl):9–11

    Google Scholar 

  14. Glasson P, Favre H (1984) Treatment of peritonitis in continuous ambulatory peritoneal dialysis patients with Co-Trimoxazole. Nephron 36:65–67

    Google Scholar 

  15. Gokal R, Francis DMA, Goodship THJ, Bint AJ, Ramos JM, Ferner RG, Proud G, Ward MK, Kerr DNS (1982) Peritonitis in continuous ambulatory peritoneal dialysis. Lancet II:1388–1391

    Google Scholar 

  16. Gruer LD, Adu D, Turney JH, Curley J, Lockington TJ, Michael J (1984) Once daily Vancomycin and Gentamycin in the treatment of CAPD peritonitis (Abstract). Kidney Int 26:531

    Google Scholar 

  17. Hächler H, Vogt K, Binswanger U, von Graevenitz A (1986) Centrifugation of 50 ml of peritoneal fluid is sufficient for microbiological examination of CAPD-Peritonitis. Infection 14:102–104

    Google Scholar 

  18. Halstenson CE, Blevins RB, Salem NG, Matzke GR (1984) Trimethoprim-sulfamethoxazole pharmacokinetics during continuous ambulatory peritoneal dialysis. (Abstract). Clinical Nephrol 22:36

    Google Scholar 

  19. Hortling L, Bonsdorff MV, Honkanen E, Kala AR (1984) Factors contributing to peritonitis in CAPD (Abstract). Kidney Int 26:565

    Google Scholar 

  20. Krothapalli R, Senekjian H, Ayus J (1983) Efficacy of intravenous Vancomycin in the treatment of gram-positive peritonitis in long-term peritoneal dialysis. American J Med 75:345–348

    Google Scholar 

  21. Leung A, Orange G, Henderson I, Sleigh J (1984) Successful use of combined intraperitoneal Azlocillin and Aminoglykoside in the treatment of dialysis associated pseudomonas peritonitis. Perit Dial Bull 4:98–101

    Google Scholar 

  22. Loeppky C, Tarka E, Everett ED (1983) Compatibility of Cephalosporins and Aminoglykosides in peritoneal dialysis fluid. Perit Dial Bull 3:128–129

    Google Scholar 

  23. Lowy FD, Hammer SM (1983) Staphylococcus epidermidis infections. Ann int Med 99:834–839

    Google Scholar 

  24. Mergeryan H (1983) Hygienisch mikrobioligische Aspekte der Peritonitis bei CAPD. Nieren- Hochdruckkr 12:483–491

    Google Scholar 

  25. Münch R, Steurer J, Lüthy R, Siegenthaler W, Kuhlmann U (1983) Serum and dialysateoncentrations of intraperitoneal Cephalothin in patients undergoing CAPD. Clinical Nephrol 20:40–44

    Google Scholar 

  26. Nielsen ME, Sorensen I, Hansen HE (1979) Peritoneal transport of Vancomycin during peritoneal dialysis. Nephron 24/6:274–277

    Google Scholar 

  27. Obermiller LE, Tzamabulus AM, Leymon P, Avasthi PS (1985) Intravenous Vancomycin as initial treatment for gram positive peritonitis in patients on chronic peritoneal dialysis. Clin Nephrology 24/5:256–260

    Google Scholar 

  28. Oreopoulos DG, Williams P, Khanna R, Vas S (1981) Treatment of peritonitis. Perit Dial Bull 1 (Suppl):17–22

    Google Scholar 

  29. Oreopoulos DG, Vas S, Khanna R (1983) Prevention of peritonitis during continuous ambulatory peritoneal dialysis. Perit Dial Bull 3 (Suppl):18–21

    Google Scholar 

  30. Parsoo I, Seedat YK, Naicker S, Kallmeyer JC (1984) Complications of continuous ambulatory peritoneal dialysis (CAPD) — a 4.5-year experiance (Abstract). Kidney Int 26:895

    Google Scholar 

  31. Paton ThW, Manuel A, Cohen LB, Walker SE (1983) The disposition of Cefazolin and Tobramycin following intraperitoneal administration in patients on continuous ambulatory peritoneal dialysis. Perit Dial Bull 3:73–76

    Google Scholar 

  32. Rawer P, Seim KE, Breithaupt H, Schütterle G (1984) I.v. Vancomycin for Staphylococcus peritonitis during CAPD (Abstract). Kidney Int 26:588

    Google Scholar 

  33. Rottembourg J, Gahl GM, Poignet JL, Mertani E, Strippoli P, Langlois P, Tranbalec P, Legrain M (1983) Severe abdominal complications in patients undergoing continuous ambulatory peritoneal dialysis. Proc EDTA (London) 20:236–242

    Google Scholar 

  34. Ruedin P, Louis F, Favre H (1984) Peritonitis in continuous ambulatory peritoneal dialysis (CAPD) patients: Evaluation of initial ambulatory treatment with Co-Trimoxazol. (Abstract). Kidney Int 26:591

    Google Scholar 

  35. Searle M, Venkat Raman G (1984) Oral treatment of CAPD peritonitis. (Abstract). Kidney Int 26:597

    Google Scholar 

  36. Singlas E, Rottembourg J, de Martin A, Collin JN, Legrain M (1981) Pharmacocinetics of Co-Trimoxazole using the peritoneal route: Consequence for the treatment of peritonitis in patients maintained on peritoneal dialysis. In: Moncrief JW, Popovich RP (Hrsg) CAPD update, Continuous Ambulatory Peritoneal Dialysis, Masson publishing USA, p 63–66

  37. Vas S (1981) Peritonitis during CAPD: a mixed bag. Perit Dial Bull 1:47–49

    Google Scholar 

  38. Vas S (1983) Microbiologic aspects of chronic ambulatory peritoneal dialysis: Kidney Int 23:83–92

    Google Scholar 

  39. Watunakunakom C (1982) The antibacterial action of Vancomycin. Rev Infect Dis 3 (Suppl):220–215

    Google Scholar 

  40. Wiliams C, Cattran D, Fenton S, Khanna R, Manuel A, Saiphoo C, Oreopoulos DG, Roscoe J (1981) Peritonitis on CAPD-three years' experience in Toronto. Perit Dial Bull 1 (Suppl):7–10

    Google Scholar 

  41. Williams P, Khanna R, Simpson H, Vas S (1982) Tobramycin blood levels of CAPD patients during peritonitis. Perit Dial Bull 2:48

    Google Scholar 

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König, U., Müller, U. & Binswanger, U. Behandlung der Peritonitis während kontinuierlich ambulanter Peritonealdialyse (CAPD) mit Co-Trimoxazol, Cefazolin oder Vancomycin. Klin Wochenschr 65, 562–570 (1987). https://doi.org/10.1007/BF01727623

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  • DOI: https://doi.org/10.1007/BF01727623

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