Summary
Hemodynamic parameters of five chronic renal failure patients have been compared intraindividually during hemodialysis, hemofiltration, and hemodiafiltration using either acetate or bicarbonate buffer. During acetate dialysis symptomatic hypotensive episodes were common. During hemofiltration with acetate buffering a satisfactory hemodynamic stability was maintained. Cardiac and circulatory compensation was found superior with bicarbonate buffering irrespective of the treatment mode.
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Aizawa Y, Ohmiri T, Imal K, Nara Y, Matsuoka M, Hirasawa Y (1977) Depressant action of acetate upon the human cardiovascular system. Clin Nephrol 8:477
Aizawa Y, Hirasawa Y, Ohmiri T et al. (1976) The peripheral hemodynamic changes following hemodialysis: acetate vs bicarbonate effect. 19th Congress of the Japan Nephrology Society [Abstr]
Aljama P, Martin-Malo A, Sanz R, Pasaloda J, Sancho E, Gomez J, Perez R, Burdiel LG, Andres E (1982) Left ventricular function during hemofiltration and hemodialysis, a comparative study. Proc EDTA 19:281
Assomull V, Vreman MJ, Weiner MW (1978) Mass balance of base equivalents during hemodialysis: importance of acid anions. Proc Clin Dial Transplant Forum 8:137
Baldamus CA, Ernst W, Lysaght MJ, Shaldon S, Koch KM (1983) Hemodynamics in hemofiltration. Int J Art Organs 6:27
Baldamus CA, Ernst W, Fassbinder W, Koch KM (1980) Differing hemodynamic stability due to differing sympathetic response; comparison of ultrafiltration hemodialysis and hemofiltration. Proc EDTA 17:205
Bosch JP, Mac Mounie E, von Albertini B, Kahn T, Glabman S, Moutoussis G (1980) Participation of red blood cells in bicarbonate transport across the dialysator. Trans Am Soc Artif Int Organs 26:343
Chamberlain JH, Seed RGFL, Barret AM (1973) The hemodynamic effects of intravenous sodium bicarbonate. Br J Anaesth 45:1231
Clancy RL, Cingolani HE, Taylor RR, Graham TP, Gilmore JP (1967) Influence of sodium bicarbonate on myocardial performance. Am J Physiol 214 (4):917
Dagel MJ, Ahmad S, Vizzo JE, Scribner BH (1982) Acetate and bicarbonate fluctuations and acetate intolerance during dialysis. Kidney Int 21:513
Graefe U, Follette WC, Vizzo GE, Goodsman LD, Scribner BH (1967) Reduction in dialysis induced morbidity and vascular instability with the use of bicarbonate. Proc Dial Transplant Forum 6:203
Hampl H, Paeprer H, Unger V, Kessel MW (1979) Hemodynamics during hemodialysis, sequential ultrafiltration and hemofiltration. J Dialysis 3:51
Hampl H, Klopp HW, Wolfgruber M, Pustelnik A, Schiller R, Kessel M, Hanefeld F (1983) Zur Pathogenese der durch Azetatdialyse induzierten kardiovaskulären und cerebralen Probleme. Nieren- und Hochdruckkrankheiten 12:132
Kirkendol PL, Devin CJ, Bower JD, Holbert RD (1977) A comparison of the cardiovascular effects of sodium acetate, sodium bicarbonate and other sources of fixed base in hemodialysis solutions. Trans Am Soc Artif Int Organs 23:399
Kirkendol PL, Pearson JE, Bower JD, Holbert RD (1978) Myocardial depressant effects of sodium acetate. Cardiovasc Res 12:127
Kveim M, Nesbakken R (1975) Utilization of exogenous acetate during hemodialysis. ASAIO 21:138
Lewis EJ, Tolchin N, Roberts JL (1980) Estimation of the metabolic conversion of acetate to bicarbonate during hemodialysis. Kidney Int 18 [Suppl 10]:51
Molnar JI, Scott JB, Fröhlich ED (1963) Local effects of various anions and pH on dog limb and coronary vascular resistance. Am J Physiol 203:125
Novello A, Kelsch RC, Easterling RF (1976) Acetate intolerance during hemodialysis. Clin Nephrol 5:28
Quellhorst E, Schuenemann B, Hildebrand U (1981) How to prevent vascular instability: hemofiltration. Proc EDTA 18:243
Sargent JA, Gotch FA (1979) Bicarbonate and carbondioxid transport during hemodialysis. ASAIO J 2:61
Shaldon S, Beau MC, Deschodt G, Ramperez P, Mion C (1980) Vascular stability during hemofiltration. Trans Am Soc Artif Int Organs 26:391
Streicher E, Schneider H (1983) Stofftransport bei Hämodiafiltration. Nieren-und Hochdruckkrankheiten 12:339
Tolchin N, Roberts JL, Haiashi J, Lewis JE (1977) Metabolic consequences of high mass transfer hemodialysis. Kidney Int 11:336
Vincent J-L, van Herwegheim J-L, Degaute JP, Berre J, Dufaye Ph, Kahn RJ (1982) Acetate-induced myocardial depression during hemodialysis for acute renal failure. Kidney Int 22:653
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Liomin, E., Schneider, H. & Streicher, E. Hämodynamik bei Hämodialyse, Hämofiltration und Hämodiafiltration Bikarbonat-vs Azetatpufferung. Klin Wochenschr 62, 911–919 (1984). https://doi.org/10.1007/BF01727441
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DOI: https://doi.org/10.1007/BF01727441