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Klinische Wochenschrift

, Volume 66, Issue 16, pp 713–717 | Cite as

Cardiac myxoma

Clinical and pathologic features in 15 cases
  • C. Schmid
  • S. Paterakis
  • J. A. Likungu
  • P. G. Kirchhoff
Originals

Summary

Neoplasms are rare cardiac findings of which myxomas comprise about 75%. We report of 15 patients, predominantly female (60%) with a mean age of 58.8 years. Male patients (40%) were 20 years younger on average.

80% of these tumors developed in the left atrium fixed to the atrial septum. In 2 patients the right ventricle and in 1 patient the right atrium was involved. No left ventricular or bilateral tumors were found. Clinical findings showed a great variety of symptoms. Often misdiagnosis was established until echocardiography was performed. Major symptoms were dyspnea (80%), elevated erythrocyte sedimentation rate (73%), arrhythmias (53%), lung edema (47%), embolization (40%) and anemia (40%).

Pathological examination and tumor genesis are still in discussion. Several theories are reported in literature: a true thrombus, thrombus organization with malignant potential, true neoplasms as well as a familiar myxoma complex may explain clinical and histological features. Our findings did not confirm only one theory but emphasize different possibilities.

Key words

Cardiac neoplasm Myxoma Thrombus formation 

Abbreviations

LA

Left atrium

RA

Right atrium

RV

Right ventricle

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References

  1. 1.
    Attar SL, Lee YC, Singleton R, Scherlis L, David R, McLaughlin JS (1980) Cardiac myxoma. Ann Thorac Surg 29:397–405Google Scholar
  2. 2.
    Bass NM, Sharratt GJP (1973) Left atrial myxoma diagnosed by echocardiography with observation on tumor movement. Br Heart J 35:1332–1335Google Scholar
  3. 3.
    Bulkey BH, Hutchins GM (1979) Atrial myxomas: a fifty year review. Am Heart J 97:639–643Google Scholar
  4. 4.
    Crafoord CL (1955) Case report. In Lam, Cr (ed.) Proceedings, International Symposium on Cardiovascular Surgery. Philadelphia, WB Saunders, pp 201–211Google Scholar
  5. 5.
    Goldberg HP, Glenn F, Dotter CT, Steinberg I (1952) Myxoma of the left atrium. Diagnosis made during life with operative and postmortem findings. Circulation 6:762–767Google Scholar
  6. 6.
    Gray IR, Williams WG (1985) Recurring cardiac myxoma. Br Heart J 53:645–649Google Scholar
  7. 7.
    Hanson EC, Gill CC, Razavi M, Loop FD (1985) The surgical treatment of atrial myxomas. J Thorac Cardiovasc Surg 89:298–303Google Scholar
  8. 8.
    Kabbani SS, Cooley DA (1973) Atrial myxoma: surgical considerations. J Thorac Cardiovasc Surg 65:731–737Google Scholar
  9. 9.
    Kelly J, Bhagwat AG (1972) Ultrastructural features of a recurrent endothelial myxoma of the left atrium. Arch Pathol 93:219–226Google Scholar
  10. 10.
    McCarthy PM, Piehler JM, Schaff HV, et al. (1986) The significance of multiple, recurrent, and “complex” cardiac myxomas. J Thorac Cardiovasc Surg 91:389–396Google Scholar
  11. 11.
    Menetrier M (1911) Un cas de cancer primitif du coeur. Press Med 183:183Google Scholar
  12. 12.
    Nasser WK, Davis RH, Dillon JC, et al. (1972) Atrial myxoma. I. Clinical and pathological features in nine cases. Am Heart J 83:694–704Google Scholar
  13. 13.
    Nitsch J, Rienmüller R (1980) Digitalisrefraktäre Herzinsuffizienz mit arteriellen Embolien und laborchemischen Entzündungszeichen. Internist 21:624–626Google Scholar
  14. 14.
    Prichard RW (1951) Tumors of the Heart: Review of the subject and report of one hundred and fifty cases. Arch Pathol 51:91–128Google Scholar
  15. 15.
    Read CR, White HJ, Murphy ML, Williams D, Flanagan WH (1974) The malignant potentially of left atrial myxoma. J Thorac Cardiovasc Surg 68:857–868Google Scholar
  16. 16.
    Saylor WR, Page DL, Hutchins GM (1975) The development of cardiac myxomas and papillary endocardial lesions from mural thrombus. Am Heart J 9:4–17Google Scholar
  17. 17.
    Shiu MF, Abrams LD (1983) Echocardiographic features of free floating thrombus mimicking right ventricular myxoma. Br Heart J 49:612–614Google Scholar
  18. 18.
    Sutton MGStJ, Mercier LA, Guillani E, Lie JT (1980) Atrial myxomas. A review of clinical experience in 40 patients. Mayo Clin Proc 55:371–376Google Scholar

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • C. Schmid
    • 1
  • S. Paterakis
    • 1
  • J. A. Likungu
    • 1
  • P. G. Kirchhoff
    • 1
  1. 1.Universitätsklinik Bonn, Herz- und GefäßchirurgieGermany

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