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Toxicity of DFP and related compounds to squids in relation to cholinesterase inhibition and detoxifying enzyme levels

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Abbreviations

ACh:

acetylcholine

AChE:

acetylcholinesterase

GhE:

cholinesterase

ChAc:

cholineacetylase (choline acetyltransferase)

DFP:

diisopropylphosphoroflouridate

217A0:

0,0-diethyl S-(2-dimethylaminoethyl) phosphorothioate

Paraoxon:

diethyl p-nitrophenylphosphate

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Dettbarn, W.D., Hoskin, F.C.G. Toxicity of DFP and related compounds to squids in relation to cholinesterase inhibition and detoxifying enzyme levels. Bull. Environ. Contam. Toxicol. 13, 133–140 (1975). https://doi.org/10.1007/BF01721726

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Keywords

  • Physostigmine
  • Paraoxon
  • Giant Axon
  • Squid Giant Axon
  • Tabun