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European Journal of Epidemiology

, Volume 11, Issue 4, pp 475–478 | Cite as

Prevalence ofLegionella pneumophila serogroup 1 antibodies in blood donors

  • Laura Franzin
  • Florinda Scramuzza
Brief Report

Abstract

The prevalence of anti-Legionella pneumophila serogroup 1 antibodies in 777 blood donors of the Turin area was determined by the indirect immunofluorescence assay (IFA) and by the microagglutination test (MA). Low titers (IFA of 1/16 and MA of 1/8) were found in 0.3% of the subjects. A statistically significant difference was not observed by sex and by age for IFA titers, but was noted by sex for MA titers of ⩾1/4 (p<0.05). The upper limit of normal titer was <1/8 by IFA and <1/4 by MA at 15% cutoff level and 1/8 by IFA and 1/4 by MA at 1% cutoff level. In conclusion, the prevalence of antibodies in the Turin area was very low; IFA titers of ⩾1/64 and MA titers of >1/16 can be considered as presumptive of infection in a single serum specimen of a patient with pneumonia; no change in the epidemiology of the disease was observed in the recent years.

Key words

Antibodies Blood donors Legionella pneumophila 

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Copyright information

© Kluwer Academic Publishers 1995

Authors and Affiliations

  • Laura Franzin
    • 1
  • Florinda Scramuzza
    • 1
  1. 1.Infectious Diseases InstituteUniversity of TurinTurinItaly

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