Abstract
ANABEL (ANalysis of Acid-Base status by Evaluating Lisp) is a prototype medical intelligent decision-support system aiming to assist clinicians in an Intensive Care Unit environment with the interpretation of blood-gas measurements. Its architecture is based on the merging of representations for declarative (domaindescriptive) and procedural (problem-solving) medical knowledge. The system performs diagnosis in two stages (tentative and differential) by first evaluating elementary computational units of procedural knowledge (procedures) and then abstracting their symbolic outputs in generating text. Thus, a ‘semantic trace’ is built which reflects the system's line of reasoning in reaching its conclusion. This paper describes the design aspects, development and clinical validation of ANABEL.
Similar content being viewed by others
Abbreviations
- ANABEL:
-
Analysis of Acid-Base status by Evaluating Lisp
- CDS:
-
Computer-assisted Decision Support
- ICU:
-
Intensive Care Unit
- MIDSS:
-
Medical Intelligent Decision Support System
References
Zarkadakis G. Development of an intelligent decision-support system for acid-base diagnosis in high-dependency units. PhD Thesis. London: City University, 1989.
Walmsley RN, Guerin MD. Disorders of fluid and electrolyte balance. London: Wright, 1984.
Rumelhart DE, Norman DA. Representation of knowledge. In: Aitenhead AM, Slack JM, eds. Issues in cognitive modelling. London: Laurence Elbroum Assoc. Lit., 1985.
Newell A. The knowledge level. Artif Intell 1982; 18: 87–127.
Paysha F. Medical diagnosis and cybernetics. Mechanisation of thought processes, NPL Symp No 10, 1959; II: 635–59.
Minsky M. A framework for representing knowledge. In: Winston P., ed. The psychology of computer vision. New York: McGraw-Hill, 1975.
Miller P. The evaluation of artificial intelligence systems in medicine. Comp Meth Prog Biomed, 1986; 22: 5–11.
Yu VL, Fagan LM, Wraith SM, Clancey WJ, Scott AC, Hannigan J, Blum RL, Buchanan BG, Cohen SN. Antimicrobial selection by a computer: a blinded evaluation by infectious disease experts. JAMA, 1979; 242: 1279–89.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Zarkadakis, G., Carson, E.R., Cramp, D.G. et al. ANABEL: Intelligent blood-gas analysis in the intensive care unit. J Clin Monit Comput 6, 167–171 (1989). https://doi.org/10.1007/BF01721029
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01721029