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Amrinone for refractory cardiogenic shock following chloroquine poisoning

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Abstract

Cardiac arrhythmias and circulatory collapse account for the high mortality reported after severe chloroquine poisoning. We have recently observed a 17-year-old man who ingested an 8 g chloroquine overdose. Cardiac arrest occurred within 1 h. Cardiogenic shock was refractory to epinephrine, dopamine and molar sodium lactate. Amrinone, a bipyridine analog, was then successfully used to improve haemodynamic conditions.

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Authors and Affiliations

  1. Département des Soins Intensifs, Cliniques St. Luc, Avenue Hippocrate, 10, B-1200, Brussels, Belgium

    Ph. Hantson, J. L. Ronveau, B. De Coninck, J. L. Horn & P. Mahieu

  2. Laboratory of Toxicology, Cliniques Universitaires St-Luc, Brussels, Belgium

    A. Hassoun

Authors
  1. Ph. Hantson
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  2. J. L. Ronveau
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  3. B. De Coninck
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  4. J. L. Horn
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  5. P. Mahieu
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  6. A. Hassoun
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Hantson, P., Ronveau, J.L., De Coninck, B. et al. Amrinone for refractory cardiogenic shock following chloroquine poisoning. Intensive Care Med 17, 430–431 (1991). https://doi.org/10.1007/BF01720684

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  • DOI: https://doi.org/10.1007/BF01720684

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