Infection

, Volume 25, Issue 5, pp 307–309 | Cite as

Prevalence of serum HGV-RNA among hemodialysis patients in Turkey

  • M. Günaydin
  • A. Bedir
  • T. Akpolat
  • I. Kuku
  • A. Pekbay
  • S. Esen
  • E. Özyilkan
  • N. Arik
  • K. Cengiz
Brief Report

Summary

A possible agent for human non-A-E hepatitis has been identified and named hepatitis G virus (HGV). The aim of this study is to evaluate the prevalence of serum HGV-RNA among hemodialysis patients in our country and the possible correlations of serum HGV-RNA with antibody to hepatitis C virus (anti-HCV), chronic liver dysfunction, number of blood transfusions, serum hepatitis B surface antigen (HBs Ag), duration of hemodialysis therapy, history of renal transplantation and patients' age and sex. Seventy-eight hemodialysis patients and 59 healthy controls were included in the study. Twenty-seven of 78 hemodialysis patients (34.6%) and two of the 59 healthy controls were serum HGV-RNA positive (p<0.01, x2=17.8). There was no significant difference between the HGV-RNA positive and HGV-RNA negative groups regarding mean duration of dialysis therapy, anti-HCV, chronic liver dysfunction, number of blood transfusions, serum HBs Ag, duration of hemodialysis therapy, history of renal transplantation and patients' age and sex. In conclusion, hemodialysis patients carry the risk for HGV infection and transmission routes and clinical significance of HGV infection in these patients remain to be defined.

Keywords

Hepatitis Infectious Disease Clinical Significance Turkey General Practice 

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Copyright information

© MMV Medizin Verlag GmbH München 1997

Authors and Affiliations

  • M. Günaydin
    • 1
  • A. Bedir
    • 3
  • T. Akpolat
    • 4
  • I. Kuku
    • 5
  • A. Pekbay
    • 1
  • S. Esen
    • 2
  • E. Özyilkan
    • 6
  • N. Arik
    • 4
  • K. Cengiz
    • 4
  1. 1.Dept. of Clinical MicrobiologyOndokuz Mayis University, School of MedicineSamsunTurkey
  2. 2.Dept. of Clinical Microbiology and Infections DiseasesOndokuz Mayis University, School of MedicineSamsunTurkey
  3. 3.Dept. of BiochemistryOndokuz Mayis University, School of MedicineSamsunTurkey
  4. 4.Dept. of NephrologyOndokuz Mayis University, School of MedicineSamsunTurkey
  5. 5.Dept. of Internal MedicineOndokuz Mayis University, School of MedicineSamsunTurkey
  6. 6.Dept. of GastroenterologyOndokuz Mayis University, School of MedicineSamsunTurkey

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