Abstract
In this study we compared the nucleotide sequence of the 5′ NC-region of the HCV genome isolated from seven patients and two blood donors from Southern Germany. We could identify two very distinct groups of isolates: the first very similar to the HCV prototype sequence (HCV1) with homology ranging from 99.5% to 98.7%; the second showing 91.7% homology to the HCV1. Group 1 isolates could be found in five patients and the two blood donors. Group 2 isolates could be found in the two other patients. Finally, we could observe neither nucleotide insertion nor deletion in the isolates described here.
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References
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Da Silva Cardoso, M., Epple, S., Koerner, K. et al. Analysing the sequence diversity of the 5′ NC-Region of HCV-isolates found in Southern Germany. Eur J Epidemiol 10, 637–640 (1994). https://doi.org/10.1007/BF01719585
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DOI: https://doi.org/10.1007/BF01719585