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Estimating the human immunodeficiency virus infection curve of intravenous drug users in Lombardia, Italy

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Abstract

We present a model to estimate the infection curve of the human immunodeficiency virus in intravenous drug users in Lombardia. We based estimates on AIDS incidence data, according to a backcalculation model accounting for ‘therapy’ and changes in the surveillance definition of AIDS.

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References

  1. de Boor C. A practical guide to splines, 1978. Springer-Verlag, New York.

    Google Scholar 

  2. Brookmeyer R, Damiano R. Statistical methods for short term projections of AIDS incidence. Statist Med 1988; 8: 23–34.

    Google Scholar 

  3. Brookmeyer R, Gail MH. Minimum size of the acquired immunodeficiency syndrome (AIDS) epidemic in the United States. Lancet 1986, ii: 1320–1322.

    Google Scholar 

  4. Brookmeyer R, Gail MH. A method for obtaining short-term projections and lower bounds on the size of the AIDS epidemic. J Am Statist Ass 1988; 83: 301–308.

    Google Scholar 

  5. Centers of Disease Control. Revision of the case definition of acquired immunodeficiency syndrome for national reporting-United States. MMWR 1985; 34: 373–375.

    Google Scholar 

  6. Centers of Disease Control. Human immunodeficiency virus infection in the United States: a review of current knowledge. MMWR 1987a; 36: 1–48.

    Google Scholar 

  7. Centers of Disease Control. Revision of the CDC surveillance case definition for acquired immunodeficiency syndrome. MMWR 1987b; 36 (1S): 1S-15S.

    Google Scholar 

  8. Centers of Disease Control. HIV prevalence estimates and AIDS case projections for the United States: report based upon a workshop. MMWR 1990; 39: 1–31.

    Google Scholar 

  9. Commissione Nazionale per la Lotta contro l'AIDS, Ministero della Sanità. Stima del numero degli infetti. In: Aggiomamento dell'epidemiologia dell'AIDS e dell'infezione da HIV in Italia al 1992, GIAIDS 1992a; 3: 127–171 (163–170).

  10. Commissione Nazionale per la Lotta contro l'AIDS, Ministero della Sanità. Il sistema di sorveglianza dell'AIDS. In: Aggiomamento dell'epidemiologia dell'AIDS e dell'infezione da HIV in Italia al 1992, GIAIDS 1992b; 3: 127–171 (141–148).

  11. Day NE, Gore SM. Prediction of the number of new AIDS cases and the number of new persons infected with HIV up to 1992: the results of ‘back projection’ methods. In: Short-term Prediction of HIV Infections and AIDS in England and Wales, 1989. London: HMSO.

    Google Scholar 

  12. DiCiccio TJ, Romano JP. A review of bootstrap confidence intervals. J R Statist Soc B 1988; 50: 338–354.

    Google Scholar 

  13. Gail MH, Brookmeyer R. Methods for projecting course of acquired immunodeficiency syndrome epidemic. JNCI 1988; 80: 900–911.

    Google Scholar 

  14. Hinkley DV. Bootstrap methods. J R Statist Soc B 1988; 50: 321–337.

    Google Scholar 

  15. Isham V. Estimation of the incidence of HIV infection-the back projection method. In: Short-term Prediction of HIV Infections and AIDS in England and Wales, 1989. London: HMSO.

    Google Scholar 

  16. Mariotto AB, Mariotti S, Pezzotti P, Rezza G, Verdecchia A. Estimation of the acquired immunodeficiency syndrome incubation period in intravenous drug users: a comparison with male homosexuals. Am J Epidemiol 1992; 135: 428–437.

    Google Scholar 

  17. Regione Lombardia, Settore Sanità e Igiene, Servizio Igiene Pubblica, 1992. AIDS incidence data recorded up to 31 December 1992.

  18. Regione Lombardia. Secondo piano regionale degli interventi per la lotta contro l'A.I.D.S. per il triennio 1987/1989 (17 dicembre 1987), 1987.

  19. Rosenberg PS, Gail MH. Backcalculation of flexible linear models of the human immunodeficiency virus infection curve. Appl Statist 1991; 40: 269–282.

    Google Scholar 

  20. Rosenberg PS, Gail MH, Carroll RJ. Estimating HIV prevalence and projecting AIDS incidence in the United States: a model that accounts for therapy and changes in the surveillance definition of AIDS. Statist Med 1992; 11: 1633–1655.

    Google Scholar 

  21. Selik RM, Buehler JW, Karon JM, Chamberland ME, Berkelman RL. Impact of the revision of the case definition of the acquired immune deficiency syndrome in the United States. J Acquir Immune Defic Syndr 1990; 3: 73–82.

    Google Scholar 

  22. Taylor JMG. Models for the HIV infection and AIDS epidemic in the United States. Statist Med 1989; 8: 45–58.

    Google Scholar 

  23. Zeger SL, Lai-Chu S, Diggle PJ. Statistical methods for monitoring the AIDS epidemic. Statist Med 1989; 8: 3–21.

    Google Scholar 

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Authors and Affiliations

  1. Istituto di Igiene e Medicina Preventiva, Università degli Studi di Milano, Milano, Italy

    Antonino Salvaggio

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  1. Antonino Salvaggio
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Salvaggio, A. Estimating the human immunodeficiency virus infection curve of intravenous drug users in Lombardia, Italy. Eur J Epidemiol 11, 127–131 (1995). https://doi.org/10.1007/BF01719476

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  • DOI: https://doi.org/10.1007/BF01719476

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