Skip to main content
Log in

Single amino acid substitutions determine mouse CD8 allotypes: epitope mapping of mouse CD8

  • Gene-antigen register
  • Published:
Immunogenetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Barber, E. K., Dasgupta, J. D., Schlossman, S. F., Trevillian, J. M., and Rudd, C. E.: The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.Proc Natl Acad Sci USA 86: 3277–3281, 1989

    Google Scholar 

  • Blank, D., Bron, C., Gabert, J., Letourneur, F., MacDonald, H. R., and Malissen, B.: Gene transfer of the Ly-3 chain gene of the mouse CD8 molecular complex: co-transfer with the Ly-2 polypeptide gene results in detectable cell surface expression of the Ly-3 antigenetic determinants.Eur J Immunol 18: 613–619, 1988

    Google Scholar 

  • Dembic, Z., Haas, W., Zamoyska, R., Parties, J. R., Steinmetz, M., and von Boehmer, H.: Transfection of the CD8 gene enhances T cell recognition.Nature 326: 510–511, 1987

    Google Scholar 

  • Gabert, J., Langlet, C., Zamoyska, R., Parries, J. R., Schmitt-Verlhust, A. M., and Malissen, B.: Reconstitution of MHC class I specificity by transfer of T cell receptor and Lyt-2 genes.Cell 50: 545–554, 1987

    Google Scholar 

  • Gorman, S. D., Sun, Y. H., Zamolyska, R., and Parties, J. R.: Molecular linkage of the Ly-3 and Ly-2 genes. Requirement of Ly-2 for Ly-3 surface expression.J Immunol 140: 3646–3653, 1988

    Google Scholar 

  • Kramer, W., Drutsa, V., Jansen, H. W., Kramer, B., Pflugfelder, M., and Fritz, H. J.: The gapped duplex DNA approach to oligonucleotide-directed mutation construction.Nucleic Acids Res 12: 9441–9456, 1984

    Google Scholar 

  • Ledbetter, J. A., Seaman, W. E., Tsu, T. T., and Herzenberg, L. A.: Lyt-2 and Lyt-3 antigens are on two different peptide subunits linked by disulfide bonds. Relationship of subunits to T cell cytolytic activity.J Exp Med 153: 1503–1516, 1981

    Google Scholar 

  • Liaw, C. W., Zamoyska, R., and Parties, J. R.: Structure, sequence, and polymorphism of the Lyt-2 T cell differentiation antigen gene.J Immunol 137: 1037–1043, 1986

    Google Scholar 

  • Nakauchi, H., Nolan, G. P., Hsu, C., Huang, H. S., and Herzenberg, L. A.: Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8.Proc Natl Acad Sci USA 82: 5126–5130, 1985

    Google Scholar 

  • Nakauchi, H., Shinkai, Y., and Okumura, K.: Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to inununoglobulin and T-cell receptor variable and joining regions.Proc Natl Acad Sci USA 84: 4210–4214, 1987

    Google Scholar 

  • Nakayama, K.-I., Shinkai, Y.-I., Okumura, K., and Nakauchi, H.: Isolation and characterization of the mouse CD8 ß-chain (Ly-3) genes: absence of an intervening sequence between V- and J-like gene segments.J Immunol 142: 2540–2546, 1989

    Google Scholar 

  • Veilette, A., Bookman, M. A., Horak, E. M., Samelson, L. E., and Bolen, J. B.: Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck.Nature 338: 257–259, 1989

    Google Scholar 

  • Wigler, M., Sweet, R., Sim, G. K., Wold, B., Pellicer, A., Lacy, E., Maniatis, T., Silverstein, S., and Axel, R.: Transformation of mammalian cells with genes from procaryotes and eucaryotes.Cell 16: 777–785, 1979

    Google Scholar 

  • Youn, H. J., Harriss, J. V., and Gottleib, P. D.: Structure and expression of the Lyt-3a gene of C.AKR mice.Immunogenetics 28: 353–361, 1988

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nakayama, Ki., Sarai, A. & Nakauchi, H. Single amino acid substitutions determine mouse CD8 allotypes: epitope mapping of mouse CD8. Immunogenetics 33, 206–209 (1991). https://doi.org/10.1007/BF01719243

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01719243

Keywords

Navigation