References
Steward, W. P. Granulocyte and granulocyte-macrophage colony-stimulating factors. Lancet 342 (1993) 153–157.
Liescher, G. J., Burgess, A. W. Granulocyte colony-stimulating factor and granulocyte-macrophage colony stimulating factor. N. Engl. J. Med. 327 (1992) 28–35, 99–106.
Stern, A. S., Podlaski, F. J., Hulmes, J. D., Pan, Y.-C. E., Quinn, P. M., Wolitzky, A. G., Familletti, P. C., Stremlo, D. L., Truitt, T., Chizzonite, R., Gately, M. K. Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells. Proc. Natl. Acad. Sci. USA 87 (1990) 6808–6812.
Kobayashi, M., Fitz, L., Ryan, M., Hewick, R. M., Clark, S. C., Chan, S., Loudon, R., Sherman, F., Perussia, B., Trinchieri, G. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biological effects on human lymphocytes. J. Exp. Med. 170 (1989) 827–845.
Germann, T., Partenheimer, A., Ruede, E. Requirements for the growth of TH1 lymphocyte clones. Eur. J. Immunol. 20 (1990) 2035–2040.
Desai, B. B., Quinn, P. M., Wolitzky, A. G., Mongini, P. K. A., Chizzonite, R., Gately, M. IL-12 receptors. II. Distribution and regulation of receptor expression. J. Immunol. 148 (1992) 3125–3132.
Gazzinelli, R. T., Hieny, S., Wynn, T. A., Wolf, S., Sher, A. Interleukin 12 is required for the T-lymphocyte-independent induction of interferon γ by an intracellular parasite and induces resistance in T-cell deficient hosts. Proc. Natl. Acad. Sci. USA 90 (1993) 6115–6119.
Tripp, C., Wolf, S., Unanue, E. R. Interleukin 12 and tumor necrosis factor α are costimulators of interferon γ production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiological antagonist. Proc. Natl. Acad. Sci. USA 90 (1993) 3725–3729.
Mosmann, T. R., Coffman, R. L. TH1 und TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Ann. Rev. Immunol. 7 (1989) 145–173.
Paul, W. E., Seder, R. A. Lymphocyte responses and cytokines. Cell 76 (1994) 241–251.
Locksley, R. M. Interleukin-12 in host defense against microbial pathogens. Proc. Natl. Acad. Sci. USA 90 (1993) 5879–5880.
Urban, J. J., Katona, I. M., Finkelmann, F. D. Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice. Proc. Natl. Acad. Sci. USA 88 (1991) 5513–5517.
Locksley, R. M., Louis, J. A. Immunology of leishmaniasis. Curr. Opin. Immunol. 4 (1992) 413–418.
Chehimi, J., Valiante, N. M., D'Andrea, A., Rengaraju, M., Rosado, Z., Kobayashi, M., Perussia, B., Wolf, S. E., Starr, S. E., Trinchieri, G. Enhancing effect of natural killer cell stimulatory factor (NKSF/Interleukin 12) on cell-mediated cytotoxicity against tumor-derived and virus-infected cells. Eur. J. Immunol. 23 (1993) 1826–1830.
Orange, J. S., Wolf, S. E., Biron, C. A. Effects of IL-12 on the response and susceptibility to experimental viral infections. J. Immunol. 152 (1994) 1253–1264.
Kanagawa, O., Vaupel, B. A., Gayama, S., Koehler, G., Kopf, M. Resistance of mice deficient in IL-4 to retrovirus-induced immunodeficiency syndrome (MAIDS). Science 162 (1993) 240–242.
Clerici, M., Lucey, D. R., Berzofsky, J. A., Pinto, L. A., Wynn, T. A., Blatt, S. P., Dolan, M. J., Hendrix, C. W., Wolf, S. F.;Shearer, G. M. Restoration of HIV-specific cell mediated immune responses by interleukin-12in vitro. Science 262 (1993) 1721–1724.
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Drews, J. Novel immunological pathways to the treatment of infections. Infection 22, 157–159 (1994). https://doi.org/10.1007/BF01716694
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DOI: https://doi.org/10.1007/BF01716694