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Dipolar cycloadditions in solid-phase organic synthesis (SPOS)

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Summary

We present a concise review of polymer-supported 1,3-dipolar cycloaddition reactions. Nitrile oxide and azomethine ylides constitute the two types of 1,3-dipoles which have been used in conjunction with solid-phase organic synthesis. These cycloaddition reactions on solid phase are generally of equal or greater efficiency than the analogous solution-phase reactions.

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  1. Department of Chemistry, University of California, 95616, Davis, CA, USA

    Eric J. Kantorowski & Mark J. Kurth

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  1. Eric J. Kantorowski
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Kantorowski, E.J., Kurth, M.J. Dipolar cycloadditions in solid-phase organic synthesis (SPOS). Mol Divers 2, 207–216 (1997). https://doi.org/10.1007/BF01715636

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