Zusammenfassung
1. Die Plasmaphospholipide von acht lebergesunden Patienten und von sechs Patienten mit akuter Hepatitis wurden dünnschichtchromatographisch getrennt und quantitativ bestimmt.
2. Die Gesamt-Plasmaphospholipide waren bei den Hepatitisfällen signifikant erhöht.
3. Die einzelnen Phospholipidfraktionen zeigten bei den Patienten mit Hepatitis charakteristische Abweichungen von der Norm: Lecithin war gegenüber der Norm deutlich erhöht, Sphingomyelin nur relativ erniedrigt, Phosphatidyläthanolamin jedoch auch absolut vermindert.
Summary
1. Phospholipids extracted from plasma of eight individuals without hepatic diseases and of six patients with acute hepatitis were separated by thinlayer chromatography and quantitatively determined.
2. The total amount of plasma phospholipids in patients with acute hepatitis was significantly increased.
3. The individual fractions of phospholipids in patients with hepatitis showed a different pattern: Lecithin was stronglyi ncreased, a relative decrease of sphingomyelin and an absolute decrease of phosphatidylaethanolamin was observed.
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Dienstl, F., Kunz, F. & Maizar, H.A. Veränderungen der Plasmaphospholipide bei akuter Hepatitis. Klin Wochenschr 44, 967–968 (1966). https://doi.org/10.1007/BF01711470
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DOI: https://doi.org/10.1007/BF01711470