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Multiple brain abscesses and bacteremia in a child due toFusobacterium necrophorum

Multiple Hirnabszesse und Bakteriämie durch Fusobacterium necrophorum bei einem Kind

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Summary

A case ofFusobacterium necrophorum bacteremia and multiple brain abscesses in a 6-year-old child following aMycoplasma pneumoniae infection is described. Brain abscess due to this microorganism has only been described in three other cases since 1977. The clinical picture was consistent with postanginal septicemia, with septic metastatic complications normally only seen in teenagers and young adults. The patient was successfully treated with a 2-month course of parenteral penicillin G and metronidazole.

Zusammenfassung

Eine „Bakteriämie“, kompliziert durch multiple Hirnabszesse, trat bei einem sechs Jahre alten Kind nach einer Atemwegsinfektion durchMycoplasma pneumoniae auf. Seit 1977 wurden nur drei Fälle von Hirnabszeß durchF. necrophorum beschrieben. Das klinische Bild war vergleichbar mit einer postanginösen Bakteriämie mit septischer Komplikation, wie sie normalerweise bei jungen Erwachsenen gefunden wird. Die parenterale Behandlung mit Penicillin-G und Metronidazol für zwei Monate führte zur Heilung.

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References

  1. De Rautlin de la Roy, Y., Toma, V., Grignon, B., Grollier, G., Paute, M. C. Abscès cérébral àFusobacterium necrophorum. Importance des conditions de prélèvement et d'analyse bactériologique (letter). Nouv. Presse Méd. 7 (1978) 3454–3455.

    Google Scholar 

  2. Eykyn, S. J. Necrobacillosis. Scand. J. Infect. Dis. 62 Suppl. (1989) 41–46.

    Google Scholar 

  3. Rathore, M. H., Barton, L. L., Dunkle, L. M. The spectrum of fusobacterial infections in children. Pediatr. Infect. Dis. J. 9 (1990) 505–508.

    Google Scholar 

  4. Sutter, V. L., Citron, D. M., Edelstein, M. A. C., Finegold, S. M. Wadsworth anaerobic bacteriology manual. 4th ed. Star Publishing Company, Belmont California 1985, pp. 85–89.

    Google Scholar 

  5. Burden, P. Fusobacterium necrophorum and Lemierre's syndrome. J. Infect. 23 (1991) 227–231.

    Google Scholar 

  6. Vogel, L. C., Boyer, K. M. Metastatic complications ofFusobacterium necrophorum sepsis. Two cases of Lemierre's postanginal septicaemia. Am. J. Dis. Child 134 (1980) 356–358.

    Google Scholar 

  7. Moreno, S., Garcia Altozano, J., Pinilla, B., Lopez, J. C., Quiros, B., Ortega, A., Bouza, E. Lemierre's disease: postanginal bacteremia and pulmonary involvement caused byFusobacterium necrophorum. Rev. Infect. Dis. 11 (1989) 319–324.

    Google Scholar 

  8. Seidenfeld, S. M., Sutker, W. L., Luby, J. P. Fusobacterium necrophorum septicemia following oropharyngeal infection. JAMA 248 (1982) 1348–1350.

    Google Scholar 

  9. Sinave, C. P., Hardy, G. J., Fardy, P. W. The Lemierre syndrome: suppurative thrombophlebitis of the internal jugular vein secondary to oropharyngeal infection. Medicine 68 (1989) 85–94.

    Google Scholar 

  10. Goldhagen, J., Alford, B. A., Prewitt, L. H., Thompson, L., Hostetter, M. K. Suppurative thrombophlebitis of the internal jugular vein: report of three cases and review of the pediatric literature. Pediatr. Infect. Dis. J. 7 (1988) 410–414.

    Google Scholar 

  11. Dagan, R., Powell, K. R. Postanginal sepsis following infectious mononucleosis. Arch. Intern. Med. 147 (1987) 1581–1583.

    Google Scholar 

  12. Donat, W. E., Mark, E. J. A 20-year-old man with diffuse pulmonary infiltrates and disseminated intravascular coagulation. N. Engl. J. Med. 326 (1992) 324–336.

    Google Scholar 

  13. Finegold, S. M. Central nervous system infections. In:Finegold, S. M. (ed.): Anaerobic bacteria in human disease. Academic Press, New York 1977, pp. 155–181.

    Google Scholar 

  14. Jadavji, T., Humphreys, R. P., Prober, C. G. Brain abscesses in infants and children. Pediatr. Infect. Dis. J. 4 (1985) 394–398.

    Google Scholar 

  15. Henry, S., DeMaria, A., McCabe, W. R. Bacteremia due to Fusobacterium species. Am. J. Med. 75 (1983) 225–231.

    Google Scholar 

  16. Jacobs, J. A., Hendriks, J. J. E., Verschure, P. D. M. M., van der Wurff, A. M., Freling, G., Vos, G. D., Stobberingh, E. E. Meningitis due toFusobacterium necrophorum subspeciesnecrophorum. Case report and review of the literature. Infection 21 (1993) 57–60.

    Google Scholar 

  17. Rennels, M. B., Woodward, C. L., Robinson, W. L., Gumbinas, M. T., Brenner, J. I. Medical cure of apparent brain abscesses. Pediatrics 72 (1983) 220–224.

    Google Scholar 

  18. Boom, W. H., Tuazon, C. U. Successful treatment of multiple brain abscesses with antibiotics alone. Rev. Infect. Dis. 7 (1985) 189–199.

    Google Scholar 

  19. Whelan, M. A., Hilal, S. K. Computed tomography as a guide in the diagnosis and follow-up of brain abscesses. Radiology 135 (1980) 663–665.

    Google Scholar 

  20. Sutter, V. L., Finegold, S. M. Susceptibility of anaerobic bacteria to 23 antimicrobial agents. Antimicrob. Agents Chemother. 10 (1976) 736–752.

    Google Scholar 

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Meis, J.F.G.M., Hoogkamp-Korstanje, J.A.A., Polder, T.W. et al. Multiple brain abscesses and bacteremia in a child due toFusobacterium necrophorum . Infection 21, 174–176 (1993). https://doi.org/10.1007/BF01710542

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  • DOI: https://doi.org/10.1007/BF01710542

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