Abstract
A case of acute hepatitis associated withCampylobacter jejuni bacteraemia is reported. Transaminase levels were increased over 50-fold in a patient with clinical features of enteritis and septicaemia.Campylobacter jejuni was isolated from blood and faecal cultures. Other infective and noninfective causes of acute hepatitis were excluded. The patient's symptoms and liver function values improved after antimicrobial therapy. Hepatitis should be considered as a complication of humanCampylobacter jejuni infection.
Similar content being viewed by others
References
Allos BM, Blaser MJ:Campylobacter jejuni and the expanding spectrum of related infections. Clinical Infectious Diseases 1995, 20: 1092–1101.
Guerrant RL, Lahita RG, Winn CW Jr, Roberts RB: Campylobacteriosis in man: pathogenic mechanisms and review of 91 bloodstream infections. American Journal of Medicine 1978, 65: 584–592.
Mertens A, De Smet M:Campylobacter cholecystitis. Lancet 1979, i: 1092–1093.
Ezpeleta C, Rojo de Ursua P, Obregon F, Goñi F, Cisterna R: Acute pancreatitis associated withCampylobacter jejuni bacteremia. Clinical Infectious Diseases 1992, 12: 1050.
Sevoian MG, Winterfield RW, Goldman LL: Avian infectious hepatitis. I. Clinical and pathological manifestations. Avian Diseases 1958, 2: 3–18.
Reddy KR, Farnum JB, Thomas E: Acute hepatitis associated withCampylobacter colitis. Journal of Clinical Gastroenterology 1983, 5: 259–262.
Humphrey KS:Campylobacter infection and hepatocellular injury. Lancet 1993, 341: 49.
Anonymous: Ischaemic hepatitis. Lancet 1985, i: 1019–1020.
Blaser MJ, Hardesty HL, Powers B, Wang WL: Survival ofCampylobacter fetus subspeciesjejuni in biological milieus. Journal of Clinical Microbiology 1980, 11: 309–313.
Drake AA, Gilchrist MJR, Washington JA II, Huizenga KA, Van Scoy RE: Diarrhoea due toCampylobacter fetus subspeciesjejuni: a clinical review of 63 cases. Mayo Clinic Proceedings 1981, 56: 414–423.
Pitkänen T, Pönkä A, Pettersson T, Kosunen TU:Campylobacter enteritis in 188 hospitalized patients. Archives of Internal Medicine 1983, 143: 215–219.
Kita E, Katsui N, Nishi K, Emoto M, Yanagase Y, Kashiba S: Hepatic lesions in experimentalCampylobacter jejuni infection of mice. Journal of General Microbiology 1986, 132: 3095–3103.
Kita E, Oku D, Hamuro A, Nishikawa F, Emoto M, Yagyu Y, Katsui N, Kashiba S: Hepatotoxic activity ofCampylobacter jejuni. Journal of Medical Microbiology 1990, 33: 171–182.
Kita E, Nishikawa F, Kamikaidou N, Nakano A, Katsui N, Kashiba S: Mononuclear cell response in the liver of mice infected with hepatotoxigenicCampylobacter jejuni. Journal of Medical Microbiology 1992, 37: 326–331.
Misawa N, Ohnishi T, Uchida K, Nakai M, Nasu T, Itoh K, Takahashi E: Experimental hepatitis induced byCampylobacter jejuni infection in Japanese quail (Coturnix coturnix japonica). Journal of Veterinary Medical Science 1996, 58: 205–210.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Korman, T.M., Varley, C.C. & Spelman, D.W. Acute hepatitis associated withCampylobacter jejuni bacteraemia. Eur. J. Clin. Microbiol. Infect. Dis. 16, 678–681 (1997). https://doi.org/10.1007/BF01708559
Issue Date:
DOI: https://doi.org/10.1007/BF01708559