A woman ingested 400 ml of leather tanning solution containing 48 g of basic chromium sulphate (CrOHSO4). This substance forms hydrogen ions and trivalent chromium when it reacts with tissue proteins. The patient died of cardiogenic shock, complicated by pancreatitis and gut mucosal necrosis and haemorrhage. There are no reported cases of toxicity due to oral ingestion of trivalent chromium. Toxicity of hexavalent and trivalent chromium is dicussed and suggestions made for management of future cases.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Tandon SK, Mathur AK, Gaul JS (1977) Urinary excretion of chromium and nickel among electroplaters and pigment industry workers. Int Arch Occupat Environ Health 40:71–76
Tsuneta Y, Oshaki Y, Kimura K, Mikami H, Abes S, Murao M (1980). Chromium content of lungs of chromate workers with lung cancer. Thorax 35:294–297
Kelly WF, Ackrill P, Day JP, O'Hara M, Tye CT, Burton I, Orton C, Harris M (1982) Cutaneous absorption of trivalent chromium: tissue levels and treatment by exchange transfusion. Br J Industr Med 39:397–400
Fristedt B, Lindqvist B, Schutz A, Ovrum P (1965) Survival in a case of acute oral chromic acid poisoning with acute renal failure treated with haemodialysis. Acta Med Scand 177:153–160
About this article
Cite this article
van Heerden, P.V., Jenkins, I.R., Woods, W.P.D. et al. Death by tanning — a case of fatal basic chromium sulphate poisoning. Intensive Care Med 20, 145–147 (1994). https://doi.org/10.1007/BF01707671
- Chromium sulphate