Summary
A unique case of IgA κ myeloma is presented. While the myeloma cells had secreted a large quantity of IgA κ monoclonal protein, they were induced to stop secreting the monoclonal protein by cyclophosphamide and vincristine, in spite of a remarkable increase in tumor burden. The absence of intracytoplasmic IgAκ was clearly evidenced by the immunofluorescence technique using anti-IgA and anti-κ monoclonal antibodies.
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Kubota, K., Kurabayashi, H., Kawada, E. et al. Nonsecretion of myeloma protein in spite of an increase in tumor burden by chemotherapy. Ann Hematol 63, 232–233 (1991). https://doi.org/10.1007/BF01703451
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DOI: https://doi.org/10.1007/BF01703451