Skip to main content
SpringerLink
Log in

Capsid protein gene sequence of feline calicivirus isolates 255 and LLK: Further evidence for capsid protein configuration among feline caliciviruses

  • Published:
Virus Genes Aims and scope Submit manuscript

Abstract

The capsid protein gene sequences are reported for two feline calicivirus (FCV) isolates, one a highly virulent isolate associated with respiratory disease, designated 255, and an isolate associated with neuromuscular disorders, designated LLK. Both capsid protein sequences conform to a previously described hypothesis wherein FCV capsid proteins may be divided into six regions based on sequence similarity among isolates. Region A corresponds to the amino-terminal area of the protein that is theoretically cleaved to produce the functional species. With a large area of sequence identity among isolates, region B contains a potential myristilated glycine and a putative ATP/GTP binding site. Region C is a short hypervariable sequence of unknown function followed by another conserved area designated region D. The E region is an area of extensive amino acid sequence hypervariability that presumably contains the antigenic determinants of the capsid protein. Region F contains the highly conserved carboxy-terminal portion of the protein.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Kahn D.E. and Gillespie J.H., Am J Vet Res32 521–531, 1971.

    Google Scholar 

  2. Gillespie J.H. and Scott F.W., Adv Vet Sci17 163–200, 1992.

    Google Scholar 

  3. Johnson R.P., Can J Vet Res56 326–330, 1992.

    Google Scholar 

  4. Bittle J.L., York C.J., Newberne J.W., and Martin M., Am J Vet Res21 547–550, 1960.

    Google Scholar 

  5. Crandell R.A., Proc Soc Exp Biol Med126 240–244, 1967.

    Google Scholar 

  6. Povey R.C., Infect Immun10 1307–1314, 1974.

    Google Scholar 

  7. Kalunda M., Lee K.M., Homes, D.F., and Gillespie J.H., Am J Vet Res36 353–356, 1975.

    Google Scholar 

  8. Burki F., Starustlea B., and Ruttner O., Infect Immun14 876–881, 1976.

    Google Scholar 

  9. Dawson S., McArdle F., Bennet, D., Carter S., Bennet, M., Ryvar R., and Gaskell R.M., Vet Rec132 346–350, 1993.

    Google Scholar 

  10. Dawson S., McArdle F., Bennet M., Carter M., Milton I.P., Turner P., Meanger J., and Gaskell R.M., Vet Rec133 13–17, 1993.

    Google Scholar 

  11. Carter M.J., Routledge E.G., and Tomes G.L., J Gen Virol70 2197–2200, 1989.

    Google Scholar 

  12. Toya Y., Masuoka K., Takahashi E., and Mikami T., Arch Virol117 173–181, 1991.

    Google Scholar 

  13. Ormerod E. and Jarrett O., J Gen Virol39 537–540, 1978.

    Google Scholar 

  14. Povey R.C. and Ingersoll J., Infect Immun11 877–885, 1975.

    Google Scholar 

  15. Kahn D.E., Hoover E.A., and Bittle J.L., Infect Immun11 1003–1009, 1975.

    Google Scholar 

  16. Knowles J.O., Dawson S., Gaskell R.M., Gaskell C.J., and Harvey C.E., Vet Rec127 125–127, 1990.

    Google Scholar 

  17. Carter M.J., Milton I.D., Meanzer J., Bennett J., Gaskell R.M., and Turner P.C., Virology190 443–448, 1992.

    Google Scholar 

  18. Carter M.J., Milton I.D., Turner P.C., Meanzer J., Bennet M., and Gaskell R.M., Arch Virol122 223–235, 1992.

    Google Scholar 

  19. Neill J.D., Virus Res17 145–160, 1990.

    Google Scholar 

  20. Neill J.D., Reardon I.M., and Heinrikson R.L., Virol65 5440–5447, 1991.

    Google Scholar 

  21. Koonin E.V., Boyko V.P., and Dolja V.V., Virology181 395–398, 1991.

    Google Scholar 

  22. Toya Y., Taniguchi Y., Takahashi E., Utagawa E., Takeda N., Miyanura K., Yamazaki S., and Mikami T., Virology183 810–814, 1991.

    Google Scholar 

  23. Seal B.S., Ridpath J.F., and Mengeling W.L., J Gen Virol74 2519–2524, 1993.

    Google Scholar 

  24. Neill J.D., Virus Res24 211–222, 1992.

    Google Scholar 

  25. Kahn D.E. and Gillespie J.H., Cornell Vet60 669–683, 1970.

    Google Scholar 

  26. Pederson N.C., Laliberte L., and Ekman S., Feline Pract13 26–35, 1983.

    Google Scholar 

  27. Crandell R.A., Fabricant C.A., and Nelson-Rees W.A., In Vitro9 176–185, 1973.

    Google Scholar 

  28. Love D.N. and Jones R.F., Arch Gesamte Virusforsch44 142–143, 1974.

    Google Scholar 

  29. Chirgwin J.M., Przybyla A.E., MacDonald R.J., and Rutter W.J., Biochemistry18 5294–5299, 1979.

    Google Scholar 

  30. Glisin V., Crkvenjakov R., and Byers C., Biochemistry13 2633–2637, 1974.

    Google Scholar 

  31. Okayama H. and Berg P., Mol Cell Biol2 161–170, 1982.

    Google Scholar 

  32. Gubler U. and Hoffman B.J., Gene25 263–269, 1983.

    Google Scholar 

  33. Kotewicz M.L., Sampson C.M., D'Alessio D.E., and Gerard G.F., Nucleic Acids Res16 265–277, 1988.

    Google Scholar 

  34. D'Alessio J.M. and Gerard G.F., Nucleic Acids Res16 1999–2014, 1988.

    Google Scholar 

  35. Hanahan D.H., in Glover D.M. (ed).DNA Cloning: A Practical Approach, Vol. I. IRL Press, Oxford, 1985, pp. 109–136.

    Google Scholar 

  36. Zhou C., Yang Y., and Jong A.Y., Biotechniques8 172–173, 1990.

    Google Scholar 

  37. Tabor S. and Richardson C.C., Proc Natl Acad Sci USA84 4767–4771, 1987.

    Google Scholar 

  38. Sanger F., Nickles S., and Carlson A.R., Proc Natl Acad Sci USA74 5463–5467, 1977.

    Google Scholar 

  39. Smith L.M., Sanders J.Z., Kaiser R.J., Hughes P., Dodd C., Connell C.R., Heines C., Kent S.B.H., and Hood L.E., Nature321 673–681, 1986.

    Google Scholar 

  40. Prober J.M., Trainor G.L., Dan R.J., Hobbs F.W., Robertson C.W., Zaqursky R.J., Cocuzza A.J., Jensen M.A., and Burmeister K., Science238 336–341, 1987.

    Google Scholar 

  41. Chow M., Newman J.F.E., Filman D., Hogle J.M., Rowlands D.J., and Brown F., Nature327 482–486, 1987.

    Google Scholar 

  42. Grand R.J.A., Biochem J258 625–638, 1989.

    Google Scholar 

  43. Walker J.E., Saraste M., Runswick M.J., and Gay M.J., EMBO J1 945–951, 1982.

    Google Scholar 

  44. Kyte J. and Doolittle R.F., J Mol Biol157 105–132, 1982.

    Google Scholar 

  45. Emini E.A., Hughs J.V., Perlow D.S., and Boger J., J Virol55 836–839, 1985.

    Google Scholar 

  46. Jameson B.A. and Wolf H., CABIOS4 181–186, 1988.

    Google Scholar 

  47. Guiver M., Littler E., Caul E.O., and Fox A.J., J Gen Virol73 2429–2433, 1992.

    Google Scholar 

  48. Milton I.D., Turner J., Teelna A., Gaskell R., Turner P.C., and Carter M.J., J Gen Virol73 2435–2439, 1992.

    Google Scholar 

  49. Shin Y.-S., Tohya Y., Oshikamo R., Kawaguchi Y., Tomonaga K., Miyazawa T., Kai C., and Mikami T., Vet Res30 17–26, 1993.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Southeast Poultry Research Laboratory, U.S.D.A., 934 College Station Rd., 30605, Athens, GA, USA

    Bruce S. Seal

  2. National Animal Disease Center, U.S.D.A., Ames, Iowa, USA

    John D. Neill

Authors
  1. Bruce S. Seal
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. John D. Neill
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Seal, B.S., Neill, J.D. Capsid protein gene sequence of feline calicivirus isolates 255 and LLK: Further evidence for capsid protein configuration among feline caliciviruses. Virus Genes 9, 183–187 (1995). https://doi.org/10.1007/BF01702662

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01702662

Key words

Search

Navigation