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Interaction of 7,10-dimethylbenz[c]acridine with deoxyribonucleic acid

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References

  • Buu-Hoi NP, Lecocq L (1944) Chemistry of inhibitions of carcinogenic hydrocarbons; synthesis of polymethylbenzacridines. Compt Rend Acad Sci 218:792–794

    Google Scholar 

  • Grimmer G, Naujack K-W, Dettbarn G (1987) Gas chromatographic determination of polycyclic aromatic hydrocarbons, aza-arenes, aromatic amines in the particle and vapor phase of mainstream and sidestream smoke of cigarettes. Toxicologe Letters 35:117–124

    Google Scholar 

  • Kamata K, Motohashi N (1986) Quantitative structure-activity relationships (QSAR) by the1H NMR spectra of methylbenz[c]acridines. Neoplasma 33:313–322

    PubMed  Google Scholar 

  • Levin W, Wood AW, Chang RI, Kumar S, Yagi H, Jerina DM, Lehr R, Conney AH (1983) Tumor-initiating activity of benz[c]acridine and twelve of its derivatives on mouse skin. Cancer Res 43:4625–4628

    PubMed  Google Scholar 

  • Lacassagne A, Buu-Hoi NP, Daudel R, Zajdela F (1956) The relation between carcinogenic activity and the physical and chemical properties of angular benz[c]acridines. Adv Cancer Res 4:315–369

    PubMed  Google Scholar 

  • Motohashi N, Kamata K (1983) A convinient method of the purification for carcinogenic and noncarcinogenic methyl-substituted benz[c]acridines. Yakugaku Zasshi 103:795–799

    PubMed  Google Scholar 

  • Nielsen T, Cleausen P, Jensen FP (1986) Determination of basic azaarenes and polynuclear aromatic hydrocarbons in airborn particulate matter by gas chromatography. Anal Chim Acta 187:223–231

    Google Scholar 

  • Okano T, Horie T, Motohashi N, Watanabe Y, Nishimiya Y (1975) Electronic interaction of carcinogenic and noncarcinogenic benz[c]acridines and DNA. Gann 66:529–537

    PubMed  Google Scholar 

  • Okano T, Horie T, Iwaizumi M, Motohashi N (1978) Formation of free radicals from carcinogenic benz[c]acridines in the presence of proteins. Gann 69:109–114

    PubMed  Google Scholar 

  • Sadler PW (1960) Application of molecular spectroscopy to relations between biological activity and structure. Chem Revs 60:575–592

    Google Scholar 

  • Sawicki E, McPherson SP, Stanley TW, Meeker J, Elbert WC (1965) Quantitative composition of the urban atomosphere in terms of polynuclear aza heterocyclic compound and aliphatic and polynuclear aromatic hydrocarbons. Int J Air Poll 9:515:-524

    Google Scholar 

  • Wakeham SG (1979) Azaarenes in recent lake sediments. Environ Sci Technol 13:1118–1123

    Google Scholar 

  • Wood AW, Chang RL, Levin W, Ryan DE, Thomas PE, Lehr RE, Kumar S, Schaefer-Ridder M, Englehardt M, Yagi H, Jerina DM (1983) Mutagenicity of diol epoxides and tetrahydroepoxides of benz[a]acridine and benz[c]-acridine in a bacteria and mammalian cells. Cancer Res 43:1656–662

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Metropolitan Research Laboratory of Public Health, 169, Tokyo, Japan

    Kunihiro Kamata

  2. Meiji College of Pharmacy, 188, Tokyo, Japan

    Noboru Motohashi

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  1. Kunihiro Kamata
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  2. Noboru Motohashi
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Kamata, K., Motohashi, N. Interaction of 7,10-dimethylbenz[c]acridine with deoxyribonucleic acid. Bull. Environ. Contam. Toxicol. 43, 534–540 (1989). https://doi.org/10.1007/BF01701931

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  • DOI: https://doi.org/10.1007/BF01701931

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