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Pathological and biochemical alterations induced by inhalation of furfural vapor in rat lung

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  1. Dutta KK, Gupta GSD, Misra Anil, Joshi A, Tandon GS, Ray PK (1988) Inhalation toxicity studies of Methyl Isocyanate (MIC) in rats: Part I Pulmonary pathology and genotoxicity evaluation. Indian J Exp Biol 26: 177–182

    PubMed  Google Scholar 

  2. Fassett DW (1963) Aldehyde and acetates In: Industrial Hygiene and Toxicology. FA Patty (ed) 2nd edition Interscience Publishers New York pp 1987

    Google Scholar 

  3. Feron VJ, Kruysse A, Dreef-Van Der Meulen HC (1979) Repeatedexposure to furfural vapour: 13 week study in syrian golden hamsters. Zentralbl Bakteriol Parasite-nkd Infektionskr Hyg Abt 1 Orig Reiche B 168: 442–451

    Google Scholar 

  4. Jollow DJ, Mitchell JR, Zampagione N, Gillette JR (1974) Bromobenzene induced liver necrosis Protective role of glutathione and evidence for 3,4 bromobenzene oxide as the hepatotoxic intermediate. Pharmacology 11: 151–156

    PubMed  Google Scholar 

  5. Kaminski M, Jonek JJ, Konecki J (1974) Behaviour of some enzymes in rat kidney in acute poisonong with furfural. Acta Histochem 48: 102–114

    PubMed  Google Scholar 

  6. Koskowska M, Skalska-Hilgier E, Szymczyk T (1982) Arginase activity following exposure to furfural. Bromatol Chem Toksykol 15: 241–247

    Google Scholar 

  7. Lowry OH, Rosebrough NJ, Farr A, Randall RJ (1951) Protein measurement withthe Folin-phenol reagent. J Biol Chem 193: 265–275

    PubMed  Google Scholar 

  8. Misra Anil, Dwivedi PD, Verma AS Gupta GSD, Dutta KK, Ray PK (1988) Interaction of furfural with microsonal detoxication system of rat lung. Presented at international workshop on detoxication held at ITRC Lucknow from Feb 24–29, 1988

  9. Mishra Anil, Gupta GSD, Agarwal D (1991) Inhalation toxicology of furfural vapours: An assesment of bioc hemical responce in rat lungs. J Appl Toxi (In press)

  10. Niosh (1979) Niosh Mannual of Analytical Methods 2nd ed US Department of Health Education & Welfare. Vol 5 pp S17

  11. Ray PK, Pandya KP, Dutta KK, Rao GS, Gupta GSD, Goel SK, Misra Anil, Siddiqui SM (1987) Subchornic toxicity of furfural doped kerosene. R&D project sponsored by Indian Oil Corporation Ltd India pp 1–50

  12. Sedived V, Flek J (1978) Biological monitoring of persons exposed to furfural vapours. J Int Arch Occup Environ Hlth 42: 41–49

    Google Scholar 

  13. Skalska-Hilgier E, Szymczyk T (1982) Effect of intoxication with furfural on rat tissue aspartate aminotransferase and alanine aminotransferase. Bromatol Chem Toksykol 15: 253–258

    Google Scholar 

  14. Sendecor G, Cochran WG (1961) In: Statistical methods. The Iowa College Press Ames pp 100

    Google Scholar 

  15. Wooton IDP (1964) Microanalysis in Medical Biochemistry. 4th ed J & A Churchill Ltd London

    Google Scholar 

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Correspondence to Anil Mishra.

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Mishra, A., Dwivedi, P.D., Verma, A.S. et al. Pathological and biochemical alterations induced by inhalation of furfural vapor in rat lung. Bull. Environ. Contam. Toxicol. 47, 668–674 (1991).

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  • Waste Water
  • Water Management
  • Water Pollution
  • Furfural
  • Biochemical Alteration