Skip to main content
Log in

Modification of benzo(a)pyrene induced chromosomal damage in mouse bone marrow by Vitamin A

  • Published:
Bulletin of Environmental Contamination and Toxicology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Alam SQ, Alam BS, Chen TW (1984) Activities of fatty acid desaturases and fatty acid composition of liver microsomes in rats fed beta-caratene and 13-cis-retinoic acid, Biochim Biophys ActA 792: 110–112.

    Google Scholar 

  • Chopra DP, Wilkoff LJ (1975) Inhibition and reversal of carcinogen induced lesions in the mouse of prostatein vitro by all transretinoic acid. Proc Am Assoc Cancer Res 16: 35.

    Google Scholar 

  • Chopra DP, Wilkoff LJ (1977) Reversal by Vitamin A analogues (retinoids) of hyper plasia induced by n′-methyl-n′-nitro-guandine in mouse prostate organ cultures. J Natl Cancer Inst 58: 922–930.

    Google Scholar 

  • Chu E, Malmgren R (1965) An inhibitory effect of Vitamin A on the induction of tumors of forestomach and cervix in the Syrian hamster by carcinogenic polycyclic hydrocarbons. Cancer Res 25: 884–887.

    Google Scholar 

  • Das UN, Devi GR, Rao KP, Rao MS (1985a) Benzo(a)pyrene and gamma radiation induced genetic damage in mice can be prevented by gamma linolenic acid but not by arachidonic acid. Nutrition Res 5: 101–104.

    Google Scholar 

  • Das UN, Devi GR, Rao KP (1985b) Prostaglandin and their precursors can modify genetic damage induced by gamma radiation and benzo(a)pyrene. Prostaglandins 29: 911–916.

    Google Scholar 

  • Davies R (1967) Effect of Vitamin A on 7,12-dimethylbenz(a)-anthracene induced papilloma in Rhino mouse skin. Cancer Res 27: 237–239.

    Google Scholar 

  • Goldstein A (1965) Biostatistics An introductory text, Macmillan, New York, p 117–124.

    Google Scholar 

  • Kensler TW, Mueller GC (1978) Retinoic acid inhibition of the comitogenic action of mezerein and phorbol ester in bovine lymphocytes. Cancer Res 38: 771–775.

    Google Scholar 

  • Kliesch U, Roupova I, Adler ID (1982) Induction of chromosome damage in mouse bone marrow by benzo(a)pyrene. Mut Res 102: 265–273.

    Google Scholar 

  • Marnett LJ, Reed GA, Dennison DJ (1978) Prostglandin synthetase dependent activation of 7,8-dihydro-7,8-dihydroxy-benzo(a)-pyrene to mutagenic derivatives. Biochem Biphys Res Commun 82: 210–216.

    Google Scholar 

  • Merriman RL, Bertram JS (1979) Reversible inhibition by retinoids of 3-methylcholanthrene-induced neoplastic transformation in C3H/10T1/2 clone 8 cells. Cancer Res 39: 1661–1666.

    Google Scholar 

  • Moon RC, Grubbs CJ, Sporn MB, Goodman DG (1977) Retinyl acetate inhibits mammary carcinogenesis induced by N-methyl-nitrosourea Nature 267: 620–621.

    Google Scholar 

  • Schmid W (1976) The micronucleus test for cytogenetic analysis, in: Hollaender A. (ed) Chemical mutagens, principles and methods for their detection, Vol 4, Plenum, New York, p 31–53.

    Google Scholar 

  • Sivarajah K, Anderson MW, Eling TE (1978) Metabolism of benzo(a)-pyrene to reactive intermediates via prostaglandin biosynthesis Life Sci 23: 2571–2578.

    Google Scholar 

  • Todaro GI, DeLacro JW, Sporn MB (1978) Retinoids block phenotypic cell transformation produced by sarcoma growth factor. Nature 276: 272–274.

    Google Scholar 

  • Weeks CE, Slaga TJ, Hennings H, Gleason GL, Bracken WM (1979) Inhibition of phorbol ester induced tumor promotion in mice by Vitamin A analogue and anti-inflamatory steroid. J Natl Cancer Inst 63: 401–406.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rao, K.P., Nandan, B.D. Modification of benzo(a)pyrene induced chromosomal damage in mouse bone marrow by Vitamin A. Bull. Environ. Contam. Toxicol. 45, 829–832 (1990). https://doi.org/10.1007/BF01701079

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01701079

Keywords

Navigation