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Detection and isolation of pentachlorophenol in oil samples associated with the Spanish toxic oil syndrome

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  1. Arrhenius E, Renberg L, Johansson L, Zetterqvist M (1977) Disturbance of microsomal detoxification mechanisms in liver by chlorophenol pesticides. Chem-Biol Interact 18: 35–46.

    Google Scholar 

  2. Arribas Jimeno S (1982) The Spanish Toxic oil Syndrome. Trends Anal Chem 1: 4–6.

    Google Scholar 

  3. Gardner AM, Yurawecz MP, Cunningham WC, Diachenko GW, Mazzola EP, Brumley WC (1983) Isolation and identification of C16 and C18 fatty acid esters of chloropropanediol in adulterated Spanish cooking oils. Bull Environ Contam Toxicol 31: 625–630.

    Google Scholar 

  4. Grandjean P, Tarkowski S (Eds.) (1984). Toxic Oil Syndrome. Mass Food Poisoning in Spain. World Health Organization, Copenhagen.

    Google Scholar 

  5. Kilbourne EM, Bernert JT Jr, Posada de la Paz M, Hill RH Jr, Abaitúa Borda I, et al. (1988) Chemical correlates of pathogenicity of oils related to the Toxic Oil Syndrome epidemic in Spain. Am J Epidemiol 127: 1210–1227.

    Google Scholar 

  6. Leighty EG, Fentiman AF Jr (1982) Conjugation of pentachlorophenol to palmitic acid by liver microsomes. Bull Environ Contam Toxicol 28: 329–333.

    Google Scholar 

  7. Nilsson CA, Norstrom A, Andersson K, Rappe C (1978) Impurities in commercial products related to pentachlorophenol. In: Pentachlorophenol (K. R. Rao, Ed.), pp. 313–324.

  8. Pascual-Castroviejo I (1988) A multisystemic disease caused by adulterated rapeseed oil. Brain Dev 10: 84–87.

    Google Scholar 

  9. Tabuenca JM (1981) Toxic allergic syndrome caused by the ingestion of rapeseed oil denatured with aniline. Lancet ii: 567–568.

    Google Scholar 

  10. Veierov D, Aharonson N (1980) Improved cleaup of large lipid samples for electron capture gas chromatographic quantitation and gas chromatographic-mass spectrometric confirmation of organochlorine residues. J Assoc Off Anal Chem 63: 202–207.

    Google Scholar 

  11. Vioque A, Ventura M (1984) Detección y cuantificación de aceites minerales contaminantes de aceites vegetales relacionados con el “Síndrome Tóxico”. Grasas y Aceites 35: 106–113.

    Google Scholar 

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Correspondence to Raimon Guitart.

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Guitart, R., Abián, J., Arboix, M. et al. Detection and isolation of pentachlorophenol in oil samples associated with the Spanish toxic oil syndrome. Bull. Environ. Contam. Toxicol. 45, 181–188 (1990).

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  • Waste Water
  • Water Management
  • Water Pollution
  • Pentachlorophenol